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Translational Research

Publications

Selected prostate cancer-related publications of APCRC-Q researchers are listed below. In addition to their work in prostate cancer, many of our researchers are involved with studies in ovarian, breast and other forms of cancer, however we have limited our selection to publications specifically relating to prostate cancer research.

2018

Egbewande FA, Sadowski MC, Levrier C, Tousignant KD, White JM, Coster MJ, Nelson CC, Davis RA. Identification of gibberellic acid derivatives that deregulate cholesterol metabolism in prostate cancer cells. Journal of Natural Products. Feb 23 [epub ahead of print] doi: 10.1021/acs.jnatprod.7b00929. PMID:29474071

Armstrong HK, Gillis JL, Johnson IRD, Nassar ZD, Moldovan M, Levrier C, Sadowski MC, Chin MY, Tomlinson Guns ES, Tarulli G, Lynn DJ, Brooks DA, Selth LA, Centenera MM, Butler LM. Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion. Scientific Reports. 2018 Feb 1:8:2090. PMID: 29391407. 

2017

Lai J, Moya L, An J, Hoffman A, Srinivasan S, Panchadsaram J, Walpole C, Perry-Keene JL, Chambers S, Yeadon T, Saunders P, Eckert A, Heathcote P, Wood G, Malone G, Samaratunga H, Collins A, Turner M, Kerr K, Lehman ML, Nelson CC, Clements JA, Batra J. A microsatellite repeat in PCA3 long non-coding RNA is associated with prostate cancer risk and aggressiveness. Scientific Reports. 2017:7:16862. PMID: 29203868

Soekmadji C, Rockstroh A, Ramm GA, Nelson CC, Russell PJ. Extracellular vesicles in the adaptive process of prostate cancer during inhibition of androgen receptor signaling by enzalutamide. Proteomics. 2017 Dec; 17(23-24). PMID: 29105980 

Evans JC, Halhotra M, Sweeney K, Darcy R, Nelson CC, Hollier BG, O'Driscoll CM. Folate targeted amphiphilic cyclodextrin with fusogenic peptide for siRNA delivery to prostate cancer. International Journal of Pharmaceutics. 2017 Oct 30;532(1):511-518. PMID: 28916296.

Soekmadji C, Corcoran NM, Oleinikova I, Jovanovic L, Australian Prostate Cancer BioResource, Ramm GA, Nelson CC, Jenster G, Russell PJ. Extracellular vesicles for personalized therapy decision support in advanced metastatic cancers and its potential impact for prostate cancer. Prostate. 2017 Oct;77(14):1416-1423. doi: 10.1002/pros.23403. PMID: 28856701.

Fuhrman-Luck RA, Silva LM, Hastie ML, Gorman JJ, Clements JA. Determining Protease Substrates within a Complex Protein Background Using the PROtein TOpography and Migration Analysis Platform (PROTOMAP). Chapter 11 in: Protein Terminal Profiling. Methods in Molecular Biology, vol 1574. Editor: Schilling O,  Humana Press, New York, NY. 2017;1574:145-170. doi: 10.1007/978-1-4939-6850-3_11. PMID:28315249.

Russell PJ, Williams ED, Taylor R, Lawrence MG, Risbridger GL. Patient-derived xenograft models of prostate tumours. Section III Chapter 2 in: Patient derived tumor xenograft (PDX) models - promise, potential and practice 1st Edition. Editors: Uthamanthil R, Tinkey PT, de Stanchia E. Elsevier. Academic Press. 2017:217-28, eBook ISBN: 9780128040614

Lophatananon A, Stewart-Brown S, Kote-Jarai Z, Olama A, Garcia SB, Neal DE, Hamdy FC, Donovan JL, Giles GG, Fitzgerald LM. Southey MC, Pharoah P, Pahsayan N, Gronberg H, Wiklund F, Aly M, Stanford JL, Brenner H, Dieffenbach AK, Arndt V, Park JY, Lin H-Y, Sellers T, Slavov C, Kaneva R, Mitev V, Batra J, Spurdle A, Clements JA, APCB Bioresource, The PRACTICAL Consortium, Easton D, Eeles RA, Muir K.  Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium. British journal of cancer. 2017 Aug 1; doi: 10.1038/bjc.2017.231. PMID: 28765617

Nowlan B, Futrega K, Brunck ME, Walkinshaw G, Flippin LE, Doran MR, Levesque J-P. HIF-1α stabilizing agent FG-4497 rescues human CD34+ cell mobilization in response to G-CSF in immuno-deficient mice. Experimental Hematology. 2017 Aug;52:50-55.e6. PMID: 28527810

Silva LM, Stoll T, Kryza T, Stephens CR, Hastie ML, Irving-Rodgers HF, Dong Y, Gorman JJ, Clements JA. Mass spectrometry-based determination of Kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency. Scientific Reports. 2017 Jul 28;7(1):6789. PMID: 28754951

Levrier C, Rockstroh A, Gabrielli B, Kavallaris M, Lehman M, Davis RA, Sadowski MC, Nelson CC. Discovery of Thalicthuberine as a Novel Antimitotic Agent from Nature that Disrupts Microtubule Dynamics and Induces Apoptosis in Prostate Cancer Cells. Cell Cycle. 2017 Jul 27:0. doi: 10.1080/15384101.2017.1356512. PMID: 28749250

Berner A, Henkel J, Woodruff MA, Saifzadeh S, Kirby G, Zaiss S, Gohlke J, Reichert JC, Nerlich M, Schuetz MA, Hutmacher DW. Scaffold-cell bone engineering in a validated preclinical animal model: Precursors vs differentiated cell source. Journal of Tissue Engineering and Regenerative Medicine. 2017 Jul;11(7):2081-2089. doi: 10.1002/term.2104 PMID: 26648044 (ePub: 2015 Dec 9)

Ashton NW, Paquet N, Shirran SL, Bolderson E, Kariawasam R, Touma C, Fallahbaghery A, Gamsjaeger R, Cubeddu L, Botting C Pollock P, O'Byrne K, Richard D. hSSB1 phosphorylation is dynamically regulated by DNA-PK and PPP-family protein phosphatases. DNA Repair. 2017 Jun 30;54:30-9 PMID: 28448822

Tse  BWC*, Volpert M*, Ratther E*, Stylianou N, Nouri M, McGowan K, Lehman ML, McPherson SJ, Roshan-Moniri M, Butler MS, Caradec J, Gregory-Evans CY, McGovern J, Das R, Takhar M, Erho N, Alshalafa M, Davicioni E, Schaeffer E, Jenkins RB, Ross AE, Karnes RJ, Den RB, Fazli L, Gregory PA, Gleave ME, Williams ED, Rennie PS, Buttyan R, Gunter JH, Selth LA, Russell PJ, Nelson CC, Hollier BG. Neuropilin-1 is up-regulated in the adaptive response of prostate tumors to androgen targeted therapies and is prognostic of metastatic progression and patient mortality. Oncogene. 2017 Jun 15;36(24):3417-3427. PMID: 28092670. *Denotes co-first authors.

Touma C, Adams MN, Ashton NW, Mizzi M, El-Kamand S, Richard DJ, Cubeddu L, Gamsjaeger R. A data-driven structural model of hSSB1 (NABP2/OBFC2B) self-oligomerization. Nucleic Acids Research. 2017 Jun 13.  doi: 10.1093/nar/gkx526. PMID: 28609781

Beatty L, Kemp E, Binnion C, Turner J, Milne D, Butow P, Lambert S, Yates P, Yip D, Koczwara B. Uptake and adherence to an online intervention for cancer-related distress: older age is not a barrier to adherence but may be a barrier to uptake. Support Care Cancer. 2017 Jun;25(6):1905-1914. PMID: 28155018

Seim I, Jeffery PL, Thomas PB, Nelson CN, Chopin LK. Whole-genome sequence of the metastatic PC3 and LNCaP human prostate cancer cell lines. G3 (Bethesda), 2017 Jun 7; 7(6):1731-1741. PMID: 28413162

O’Byrne KJ, Richard DJ. Nucleolar caspase-2: Protecting us from DNA damage. Journal of Cell Biology. 2017 Jun 5;216(6):1521-1523. PMID: 28500181

Kryza T, Silva LM, Bock N, Fuhrman-Luck RA, Stephens CR, Gao J, Samaratunga H, Australian Prostate Cancer BioResource, Lawrence MG, Hooper JD, Dong Y, Risbridger GP, Clements JA, Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells. Molecular Oncology. 2017 May 16. doi: 10.1002/1878-0261.12075. PMID: 28510269

Kulansinghe A, Perry C, Kenny L, Warkiani ME, Nelson C, Punyadeera C, PD-L1 expressing circulating tumour cells in head and neck cancers. BMC Cancer. 2017 May 16;17(1):333. doi: 10.1186/s12885-017-3316-3. PMID: 28511705

Croft LV, Ashton NW, Paquet N, Bolderson E, O’Byrne KJ, Richard DJ. hSSB1 associates with and promotes stability of the BLM helicase. BMC Molecular Biology. 2017 May 15;18(1):13. PMID: 28506294

Pandey S, Walpole C, Cabot PJ, Shaw PN, Batra J, Hewavitharana AK. Selective anti-proliferative activities of Carica papaya leaf juice extracts against prostate cancer. Biomedicine & Pharmacotherapy. 2017 May;89:515-523. PMID: 28249253.

Martine LC, Holzapfel BM, McGovern JA, Wagner F, Quent VM, Hesami P, Wunner FM, Vaquette C, De-Juan-Pardo EM, Brown TD, Nowlan B, Wu DJ, Hutmacher CO, Moi D, Oussenko T, Piccinini E, Zandstra PW, Mazzieri R, Levesque J-P, Dalton PD, Taubenberger AV, Hutmacher DW. Engineering a humanized bone organ model in mice to study bone metastases. Nature Protocols.  2017 Apr;12(4):639-663. doi: 10.1038/nprot.2017.002. PMID: 28253234.

Muerza-Cascante ML, Shokoohmand A, Khosrotehrani K, Haylock D, Dalton P, Hutmacher DW, Loessner D. Endosteal-like extracellular matrix expression on melt electrospun written scaffolds. Acta Biomaterialia. 2017 Apr 1; 52:145-158. PMID: 28017869

Futrega K, Atkinson K, Lott WB, Doran MR. Spheroid Coculture of Hematopoietic Stem/Progenitor Cells and Monolayer Expanded Mesenchymal Stem/Stromal Cells in Polydimethylsiloxane Microwells Modestly Improves In Vitro Hematopoietic Stem/Progenitor Cell Expansion. Tissue Engineering Part C: Methods. 2017 Apr;23(4):200-18. PMID: 28406754

Maugham M, Thomas P, Crisp G, Philp L, Shah E, Herington A, Chen C, Gregory L, Nelson C, Seim I, Jeffery P, Chopin L. Insights from engraftable immunodeficient mouse models of hyperinsulinaemia. Scientific Reports, 2017 Mar 28;7(1):491. doi:10.1038/s41598-017-00443-x. PMID: 28352127

Nouri M, Caradec J, Lubik AA, Li N, Hollier BG, Takhar M, Altimirano-Dimas M, Chen M, Roshan-Moniri M, Butler M, Lehman M, Bishop J, Truong S, Huang S-C, Cochrane D, Cox M, Collins C, Gleave M, Erho N, Alshalafa M, Davicioni E, Nelson C, Gregory-Evans S, Karnes RJ, Jenkins RB, Klein EA, Buttyan R. Therapy-induced developmental reprogramming of prostate cancer cells and acquired therapy resistance. Oncotarget. 2017 Mar 21;8(12):18949-18967. doi: 10.18632/oncotarget.14850. PMID: 28145883

Lin HY, Chen DT, Huang PY, Liu YH, Ochoa A, Zabaleta J, Mercante DE, Fang Z, Sellers TA, Pow-Sang JM, Cheng CH, Eeles R, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Hamdy F, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau SN, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Kaneva R, Batra J, Teixeira MR, Pandha H, Lu YJ, PRACTICAL Consortium, Park JY. SNP interaction pattern identified (SIPI): an intensive search for SNP-SNP interaction patterns. Bioinformatics. 2017 Mar 15;33(6):822-833. PMID: 28039167

Seim I, Crisp G, Shah ET, Jeffery PL, Chopin LK. Abundant ghrelin gene expression by monocytes: putative implications for fat accumulation and obesity. Obesity Medicine. 2017 Mar; 5:1-3. PMID: Not available.

Luu HN, Lin HY, Sorensen KD, Ogunwobi OO, Kumar N, Chronokur G, Phelan C, Jones D, Kidd L, Batra J, Yamoah K, Berglund A, Rounbehler RJ, Yang M, Lee SH, Kang N, Kim SJ, Park JY, Di Pietro G. miRNAs associated with prostate cancer risk and progression. BMC Urology. 2017 Mar 20;17(1):18. PMID: 28320379

Das R, Gregory PA, Fernandes R, Denis I, Wang Q, Townley SL, Zhao S, Hanson AR, Pickering MA, Armstrong HK, Lokman NA, Chi KN, Ramshaw HS, Williams ED, Zoubeidi A, Goodall GJ, Feng FY, Butler LM, Tilley WD, Selth LA. MicroRNA-194 promotes prostate cancer metastasis by inhibiting SOCS2. Cancer Research. 2017 Feb 15; 77(4):1021-1034. PMID: 28011622

Chan RJ, Yates P, McCarthy AL. The development and preliminary testing of an instrument for assessing fatigue self-management outcomes in patients with advanced cancer. Cancer Nursing. 2017 Jan/Feb;40(1):48-57. PMID: 26926156

Selth LA, Das R, Townley SL, Centenera MM, Stylianou N, Sweeney K, Soekmadji C, Jovanovic L, Nelson CC, Zoubeidi A, Butler LM, Goodall GJ, Hollier BG, Gregory PA, Tilley WD. A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer. Oncogene. 2017 Jan 5;36(1):24-34. doi: 10.1038/onc.2016.185 PMID: 27270433.

Levrier C, Sadowski MC, Rockstroh A, Gabrielli B, Kavallaris M, Lehman M, Davis RA, Nelson CC. 6-acetoxy-anopterine (6-AA): A novel structure class of mitotic inhibitor disrupting microtubule dynamics in prostate cancer cells. Molecular Cancer Therapeutics. 2017 Jan;16(1):3-15. doi: 10.1158/1535-7163.MCT-16-0325. PMID: 27760837. 

Brunner C, Davies NM, Martin RM, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles G, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Donovan J, Hamdy FC, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H, PRACTICAL Consortium, Zuccolo L. Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study. International Journal of Cancer. 2017 Jan 1;140(1):75-85. PMID: 27643404.

Taylor AE, Martin RM, Geybels MS, Stanford JL, Shui I, Eeles R, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pashayan N, Khaw KT, Blot W, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H, PRACTICAL Consortium, Donovan J, Muafo MR. Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis. International Journal of Cancer. 2017 Jan 15;140(2):322-328. PMID: 27741566.

Doran M, Barnett A, Leach J, Lott W, Page K, Grant W. Can video improve grant review quality and lead to more reliable ranking? Research Ideas and Outcomes. 2017;3:e11931 PMID: Not available

2016

Nicholson C, Vela I, Williams ED. Prostate Cancer Metastasis. Chapter 3 in: Introduction to Cancer Metastasis. Editor: Ahmad A. Elsevier Academic Press; 2016 Dec, eBook ISBN: 9780128040331. Hardcover ISBN: 9780128040034

Wibowo M, Wang Q, Holst J, White JM, Hofmann A, Davis RA. Dihydro-β-agarofurans from the Australian Endemic Rainforest Plant Denhamia pittosporoides Inhibit Leucine Transport in Prostate Cancer Cells. Asian Journal of Organic Chemistry. 2016, 5, 1461-1466.

Russell PJ, Williams ED, Taylor R, Lawrence MG, Risbridger GL. Patient-derived xenograft models of prostate tumours. Section III Chapter 2 in: Patient derived tumor xenograft (PDX) models - promise, potential and practice 1st Edition. Editors: Uthamanthil R, Tinkey PT, de Stanchia E. Elsevier. Academic Press. Accepted for release 01 November 2016. Print Book ISBN :9780128040102

Wu JM, Doonan BB, Hsieh TC, Ling MT. Recent advances and challenges in studies of control of cancer stem cells and the gut microbiome by Trametes-derived polysaccharopeptide PSP. International Journal of Medicinal Mushrooms. (2016) In press.

Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM, The Australian Prostate Cancer BioResource, Hill MM, Nelson CC. Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Oncotarget, (2016 Aug 8);5. [ePub Ahead of Print] PMID: 27521215

Fuhrman-Luck RA, Stansfield SH, Stephens CR, Loessner D, Clements JA. Prostate Cancer-Associated Kallikrein-Related Peptidase 4 Activates Matrix Metalloproteinase-1 and Thrombospondin-1. Journal of Proteome Research (2016 Aug 5);15(8):2466-2478. PMID: 27378148

Poh PS, Chhaya MP, Wunner FM, De-Juan-Pardo EM, Schilling AF, Schantz JT,  van Griensven M, Hutmacher DW, Polylactides in additive biomanufacturing, Advanced Drug Delivery Reviews. (2016 Aug 2). PMID: 27492211

Joshi A, Nicholson C, Hutchinson A, Tevz G, Hollier B, McPherson S, Rhee H, Williams E, Vela I, Prostate cancer xenograft in vitro culture using organoid technology, ANZUP Annual Scientific Meeting, Brisbane, Asia-Pacific Journal of Clinical Oncology, (2016 Jul);12(S3):36.

Rhee H, Thomas P, Shepherd B, Greenslade S, Vela I, Russell PJ, Nelson C, Wood S, Heathcote P. PSMA PET improves diagnostic accuracy of mpMRI in localized prostate cancer as confirmed by whole mount histopathology: Implications for selection and assessment for active surveillance and focal therapy, ANZUP Annual Scientific Meeting, Brisbane, Asia-Pacific Journal of Clinical Oncology, (2016 Jul);12(S3):40.

Rhee H, Gunter J, Jovanovic L, Williams E, Hollier B, Vela I, Wood S, Ho K, Nelson C. Update on Androgen Deprivation Therapy and Adjuvant Metformin (ADMET) trial for men with treatment naïve metastatic prostate cancer. ANZUP Annual Scientific Meeting, Brisbane, Asia-Pacific Journal of Clinical Oncology (2016 July);12(S3):40-41.

Patel A, Rhee H, Heathcote P, Lawson M, Preston J, Vela I, Pryor D, Lehman M, Wood S.  Outcomes of salvage lymph node dissection for oligometastatic recurrent prostate cancer after radical prostatectomy: Results of a single-institution Multidisciplinary Team series. ANZUP Annual Scientific Meeting, Brisbane, Asia-Pacific Journal of Clinical Oncology, (2016 July);12(S3):38.

Kanagarajah A, Rhee H, Vela I, Lawson M, Munns J, McCaffrey E, Lehman M, Pryor D, Malone G, Preston J, Chung E, Heathcote P, Wood S, Multidisciplinary Team approach to interpreting PSMA PET data in men with prostate cancer.  ANZUP Annual Scientific Meeting, Brisbane, Asia-Pacific Journal of Clinical Oncology, (2016 Jul);12(S3):36.

Bourcy M, Suarez-Carmona M, Lambert J, Francart ME, Schroeder H, Delierneux C, Skrypek N, Thompson EW, Jerusalem G, Berx G, Thiry M, Blacher S, Hollier BG, Noel A, Oury C, Polette M, Gilles C. Tissue factor induced by epithelial-mesenchymal transition triggers a pro-coagulant state that drives metastasis of circulating tumor cells. Cancer Research. (2016 Jul 15);76(14):4270-4282. PMID: 27221703

Kashyap AS, Shooter GK, Shokoohmand A, McGovern J, Sivaramakrishnan M, Croll TI, Cane G, Leavesley DI, Söderberg O, Upton Z, Hollier BG. Antagonists of IGF:Vitronectin interactions inhibit IGF-I-induced breast cancer cell functions. Molecular Cancer Therapeutics. (2016 Jul);15(7):1602-13. PMID: 27196774

Werden SJ, Sphyris N, Sarkar TR, Paranjape AN, LaBaff AM, Taube JH, Hollier BG, Ramirez-Peña EQ, Soundararajan R, Den Hollander P, Powell E, Echeverria G, Miura N, Chang JT, Piwnica-worms H, Rosen JM, SA Mani. Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth. Oncogene. (2016 Jun 13), [Epub ahead of print] PMID: 27292262    

Wu AC, He Y, Broomfield A, Paatan NJ, Harrington BS, Tseng HW, Beaven EA, Kiernan DM, Swindle P, Clubb AB, Levesque JP, Winkler I, Ling MT, Srinivasan B, Hooper JD, Pettit AR. CD169(+) macrophages mediate woven bone formation in skeletal lesions of prostate cancer. Journal of Pathology, (2016 Jun); 239(2):218-30. PMID: 27174786 

Selth LA, Das R, Townley SL, Centenera MM, Stylianou N, Sweeney K, Soekmadji C, Jovanovic L, Nelson CC, Zoubeidi A, Butler LM, Goodall GJ, Hollier BG, Gregory PA, Tilley WD. A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer. Oncogene. (2016 Jun 6). [Epub ahead of print]. PMID: 27270433.

Quent VMC, Theodoropoulos C, Hutmacher DW, Reichert JC. Differential osteogenicity of multiple donor-derived human mesenchymal stem cells and osteoblasts in monolayer, scaffold-based 3D culture and in vivo. Biomedizinische Technik. (2016 Jun);613:253-266. PMID: 25781662

Wagner F, Holzapfel BM, Thibaudeau L, Straub M, Ling MT, Grifka J, Loessner D, Levesque JP, Hutmacher DW. A validated preclinical animal model for primary bone tumor research. Journal of Bone and Joint Surgery - American Volume. (2016 Jun);9811:916-925. PMID: 27252436

Bonilla C, Lewis SJ, Rowlands MA, Gaunt TR, Davey Smith G, Gunnell D, Palmer T, Donovan JL, Hamdy FC, Neal DE, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Grönberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H, Lathrop M, Martin RM, Holly JMP. Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels. International Journal of Cancer. (2016 Jun 23);1397:1520-1533. PMID: 27225428

Bull CJ, Bonilla C, Holly JMP, Perks CM, Davies N, Haycock P, Yu OHY, Richards JB, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, MacInnis RJ, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Micheal A, Pandha H, Smith GD Lewis SJ,  Martin, RM, PRACTICAL Consortium. Blood lipids and prostate cancer: a Mendelian randomization analysis. Cancer Medicine. (2016) Jun;5(6):1125-1136. PMID: 26992435

Philp LK, Day TK, Butler MS, Laven-Law G, Jindal S, Hickey TE, Scher HI, Butler LM, Tilley WD. Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha (SGTA) Ablation Limits Offspring Viability and Growth in Mice. Scientific Reports. (2016 Jun 30);6:28950. PMID: 27358191

de Veer SJ, Swedberg JE, Brattsand M, Clements JA, Harris JM. Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors. Biological Chemistry. (2016 Jun 24); [Epub ahead of print] PMID: 26894578

Pham T, Sadowski MC, Li H, Richard DJ, d'Emden MC, Richard K. Advances in Hormonal Therapies for Hormone Naïve and Castration-Resistant Prostate Cancers with or without Previous Chemotherapy. Experimental Hematology & Oncology (2016 Jun 22);5:15. PMID: 27340608

Pelekanos RA, Sardesai VS, Futrega K, Lott WB, Kuhn M, Doran MR. Isolation and expansion of mesenchymal stem/stromal cells derived from human placenta tissue. Journal of Visualized Experiments. (2016 Jun 6);2016(112). PMID: 27340821

Panchadsaram J, Tevz G, Stylianou N, Hollier B, Nelson C, Williams E, Clements J, Batra J. A prostate cancer risk associated polymorphism regulates androgen mediated regulation of a novel long noncoding RNA, IRX4lncRNA.  18th European Congress of Endocrinology, Munich, Germany, European Society of Endocrinology. Endocrine Abstracts, (2016 May);41:EP777. 

Rhee H, Thomas P, Shepherd B, Greenslade S, Vela I, Russell P, Nelson C, Chung E, Wood S, Heathcote P. Prostate Specific Membrane Antigen Positron Emission Tomography (PSMA PET) may improve the diagnostic accuracy of multiparametric Magnetic Resonance Imaging in localized prostate cancer as confirmed by whole mount histopathology. The Journal of Urology. (2016 May 21). [Epub ahead of print] PMID: 27220897

Gusev A, Shi H, Kichaev G, Pomerantz M, Li F, Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Zheng W, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJM, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Witte JS, Casey G, Kaggwa S, Cook MB, Stram DO, Blot WJ, Eeles RA, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Southey MC, Fitzgerald LM, Gronberg H, Shokoohmand A, Bock N, Clements JA, Hutmacher DW. An advanced bioengineered 3D model mimicking prostate cancer-induced bone metastasis microenvironment. Frontiers in Bioengineering and Biotechnology. 2016 Conference Abstract: 10th World Biomaterials Congress. (2016 May)

Wibowo M, Levrier C, Sadowski M, Nelson C, Wang Q, Holst J, Healy P, Hofmann A, Davis R. "Bioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis" Journal of Natural Products, DOI 10.1021/acs.jnatprod.6b00190, Epub 27 April 2016 PMID: 27120798

Brown TD, Dalton PD, Hutmacher DW. Melt electrospinning today: An opportune time for an emerging polymer process. Progress in Polymer Science. (2016 May); 56:116-166.

Hutchinson A, Nicholson C, Williams E, Vela I. In vitro culture of prostate cancer xenografts using organoid technology. USANZ Annual Scientific Meeting, Gold Coast, British Journal of Urology International, (2016 Apr);117(S3, SI):71. PMID: 27073124

 Shah E, Upadhyaya A, Philp LK, Tang T, Skalamera D, Gunter J, Nelson CC, Williams ED, Hollier BG. Repositioning “old” drugs for new causes: identifying new inhibitors of prostate cancer cell migration and invasion. Clin Exp Metastasis. 2016 Apr; 33(4):385-99. doi: 10.1007/s10585-016-9785-y; PMID: 26932199

Futrega K, Yu J, Jones JW, Kane MA, Lott WB, Atkinson K, Doran MR. Polydimethylsiloxane (PDMS) modulates CD38 expression, absorbs retinoic acid and may perturb retinoid signalling. Lab on a Chip - Miniaturisation for Chemistry and Biology. (2016 Apr 21);16(8):1473-1483. PMID: 27008339

Loessner D, Meinert C, Kaemmerer E, Martine LC, Yue K, Levett PA, Klein TJ, Melchels FPW, Khademhosseini A, Hutmacher DW. Functionalization, preparation and use of cell-laden gelatin methacryloyl-based hydrogels as modular tissue culture platforms. Nature Protocols. (2016 Apr);114:727-746. PMID: 26985572

Bonilla C, Lewis SJ, Martin RM, Donovan JL, Hamdy FC, Neal DE, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H, Lathrop M, Smith GD. PRACTICAL Consortium. Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort. BMC Medicine. (2016 Apr 4);14:66. PMID: 27044414

Rhee H, Vela I, Chung E. Metabolic syndrome and prostate cancer: a review of complex interplay amongst various endocrine factors in the pathophysiology and progression of prostate cancer. Hormones and Cancer. (2016 Apr);7(2):75-83. PMID: 26546071

Wiklund F, Aly M, Henderson BE, Schleutker J, Wahlfors T, Tammela TLJ, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Teerlink C, Brenner H, Dieffenbach AK, Arndt V, Park JY, Sellers TA, Lin HY, Slavov C, Kaneva R, Mitev V, Batra J, Spurdle A, Clements JA, Teixeira MR, Pandha H, Michael A, Paulo P, Maia S, Kierzek A, Conti DV, Albanes D, Berg C, Berndt SI, Campa D, Crawford ED, Diver WR, Gapstur SM, Gaziano JM, Giovannucci E, Hoover R, Hunter DJ, Johansson M, Kraft P, Le Marchand L, Lindström S, Navarro C, Overvad K, Riboli E, Siddiq A, Stevens VL, Trichopoulos D, Vineis P, Yeager M, Trynka G, Raychaudhuri S, Schumacher FR, Price AL, Freedman ML, Haiman CA, Pasaniuc B. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nature Communications. (2016 Apr 7);7:10979. PMID: 27052111

Rhee H, Gunter J , Jovanovic L, Williams E, Hollier B, Nelson C, Vela I. MP07-18 Persistence of Circulating Tumour Cells (CTCs) in men treated with Androgen Deprivation Therapy can be used to enrich and propagate temporary personalized cell lines. Journal of Urology, (2016 Apr);195(4, SS):E83-E84.

Rhee H, Gunter J, Jovanovic L, Williams E, Hollier B, Nelson C, Vela I, Delivery of precision medicine in advanced prostate cancer using circulating tumour cells. European Urology Supplements, (2016);15(3);e568.

Rhee H, Thomas P, Shepherd B, Greenslade S, Vela I, Russell P, Nelson C, Chung E, Wood S, Heathcote P. 568 PSMA PET improves diagnostic accuracy of mpMRI in localized prostate cancer as confirmed by whole mount histopathology: implications for selection and assessment for active surveillance and focal therapy. European Urology Supplements, (2016 Mar);15(3);e568.

Yates P, Danette L, Monterosso L, Aranda S, Liu W, Graves N. Impact of specialist prostate cancer nurses on patient reported and health service outcomes: A comparative effectiveness study. Oncology Nursing Forum (2016 Mar);43(2):122-123.

You J, Wilcox M, Fitzgerald A, Schiller B, Cozzi PJ, Russell PJ, Walsh BJ, Wasinger VC, Graham PH, Yong L. Absolute quantification of human tear lactoferrin using multiple reaction monitoring technique with stable-isotopic labelling. Analytical Biochemistry (2016 Mar);496:30-34. PMID: 26717899

Kirby GTS, White LJ, Steck R, Berner A, Bogoevski K, Qutachi O, Jones B, Saifzadeh S, Hutmacher DW, Shakesheff KM, Woodruff MA. Microparticles for sustained growth factor delivery in the regeneration of critically-sized segmental tibial bone defects. Materials. (2016 Mar 31);9(4):259.

Kryza T, Silva Munasinghage L, Loessner D, Heuzé-Vourc’h N, Clements JA. The kallikrein-related peptidase family: dysregulation and functions during cancer progression, (Review). Biochimie. (2016 Mar);122:283-99. PMID: 26343558

Jaroszewicz J, Kosowska A, Hutmacher D, Swieszkowski W, Moskalewski S. Insight into characteristic features of cartilage growth plate as a physiological template for bone formation. Journal of Biomedical Materials Research-Part A. (2016 Feb);104(2):357-366. PMID: 26453900

Jin W, Shah ET, Penington CJ, McCue SW, Chopin LK, Simpson MJ. Reproducibility of scratch assays is affected by the initial degree of confluence: Experiments, modelling and model selection. Journal of Theoretical Biology. (2016 Feb 16);390:136-145. PMID: 26646767

Ryan SL, Baird AM, Vaz G, Urquhart AJ, Senge M, Richard, DJ, O'Byrne KJ, Davies AM. Drug discovery approaches utilizing three-dimensional cell culture. Assay and Drug Development Technologies. (2016 Jan-Feb);14(1):19-28. PMID: 26866750 

Tevz G, McGrath S, Demeter R, Magrini V, Jeet V, Rockstroh A, McPherson S, Lai J, Bartonicek N, An J, Batra J, Dinger ME, Lehman ML, Williams ED, Nelson CC. Identification of a novel fusion transcript between human relaxin-1 (RLN1) and human relaxin-2 (RLN2) in prostate cancer. Molecular and Cellular Endocrinology 2016 Jan 15;420:159-68. doi: 10.1016/j.mce.2015.10.011; PMID: 26499396

Tang K-D, Holzapfel BM, Liu J, Lee TKW, Ma S, Jovanovic L, An J, Russell PJ, Clements JA, Hutmacher DW, Ling M-T. Tie-2 regulates the stemness and metastatic properties of prostate cancer cells. Oncotarget 2016 Jan 19;7(3):2572-84. doi: 10.18632/oncotarget.3950; PMID: 25978029

 Tang KD, Liu J, Jovanovic L, An J, Hill MM, Vela I, Lee LKW, Ma S, Nelson C, Russell PJ, Clements JA, Ling MT. Adipocytes promote prostate cancer stem cell self-renewal through amplification of the cholecystokinin autocrine loop. Oncotarget. (2016 Jan 26);7(4):4939-48. PMID: 26700819

Fountain S, Windolf M, Henkel J, Tavakoli A, Schuetz MA, Hutmacher DW, Epari DR. Monitoring healing progression and characterizing the mechanical environment in preclinical models for bone tissue engineering. Tissue Engineering Part B: Reviews. (2016 Jan);22(1):1937-3376. PMID: 26507933

Bishop DP, Clases D, Fryer F, Williams E, Wilkins S, Hare DJ, Cole N, Karst U, Doble PA. Elemental bio-imaging using laser ablation-triple quadrupole-ICP-MS. Journal of Analytical Atomic Spectrometry. (2016 Jan);311:197-202.

Poh PSP, Hutmacher DW, Holzapfel BM, Solanki AK, Stevens MM, Woodruff MA. In vitro and in vivo bone formation potential of surface calcium phosphate-coated polycaprolactone and polycaprolactone/bioactive glass composite scaffolds. Acta Biomaterialia. (2016 Jan);30:319-333. PMID: 26563472

Poh PSP, Hutmacher DW, Holzapfel BM, Solanki AK, Woodruff MA. Data for accelerated degradation of calcium phosphate surface-coated polycaprolactone and polycaprolactone/bioactive glass composite scaffolds. Data in Brief. (2016 Jan);7:923-926. PMID: 27081669

Bock N, Dargaville TR, Kirby GT, Hutmacher DW, Woodruff MA, Growth Factor-loaded microparticles for tissue engineering: the discrepancies of in vitro characterization assays. Tissue Engineering Part C: Methods, (2016 Jan);22(2):142-154. PMID: 26654547

Paquet N, Adams MN, Ashton NW, Touma C, Gamsjaeger R, Cubeddu L, Leong V, Beard S, Bolderson E, Botting CH, O'Byrne KJ, Richard DJ. hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress. Scientific Reports. (2016);6:27446. PMID: 27273218

Teleni L, Chan RJ, Chan A, Isenring EA, Vela I, Inder WJ, McCarthy AL. Exercise improves quality of life in androgen deprivation therapy treated prostate cancer: Systematic review of randomised controlled trials. Endocrine-Related Cancer. (2016);232:101-112. PMID: 26584972

Holzapfel NP, Holzapfel BM, Theodoropoulos C, Kaemmerer E, Rausch T, Feldthusen J, Champ S, Clements JA, Hutmacher DW, Loessner D. Lycopene's effects on cancer cell functions within monolayer and spheroid cultures. Nutrition and Cancer. (2016);682:350-363. PMID: 27015041

Beatty L, Kemp E, Butow P, Turner J, Milne D, Yates P, Yip D, Lambert S,  Koczwara B. Finding my way: uptake and predictors of adherence to an online psychological intervention for cancer-related distress. Supportive Care in Cancer (2016) 24(S1):S175

Ranse K, Yates P, Coyer F. Modelling end-of-life care practices: Factors associated with critical care nurse engagement in care provision. Intensive and Critical Care Nursing. (2016);33:48-55. PMID: 26846173

Alexander KE, Cooper BA, Paul SM, Yates P, Aouizerat BE, Miaskowski C. Phenotypic and molecular characteristics associated with various domains of quality of life in oncology patients and their family caregivers. Quality of Life Research. (2016):1-16. PMID: 27160108

Chan RJ, Yates P, McCarthy AL. The development and preliminary testing of an instrument for assessing fatigue self-management outcomes in patients with advanced cancer. Cancer Nursing. (2016) (epub ahead of print). PMID: 26926156

McMillan K, Butow P, Turner J, Yates P, White K, Lambert S, Stephens M, Lawsin C. Burnout and the provision of psychosocial care amongst Australian cancer nurses. European Journal of Oncology Nursing. (2016);22:37-45. PMID: 27179891

Sternberg IA, Vela I, Scardino PT. Molecular profiles of prostate cancer: To treat or not to treat. Annual Review of Medicine (2016).67:119-135.

Szulkin R, Karlsson R, Whitington T, Aly M, Gronberg, H, Eeles RA, Easton DF, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Southey MC, Fitzgerald LM, Henderson BE, Schumacher FR, Haiman CA, Sipeky C, Tammela TJ, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah PDP, Pashayan N, Khaw K-T, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Lubinski J, Kluzniak W, Cannon-Albright L, Brenner H, Herrmann V, Holleczek B, Park JY, Saunders EJ, Dadaev T, Leongamornlert DA, Al Olama AA, Benlloch S, Giles GG, Wiklund F, Grönberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pasayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau SN, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Teixeira MR, Pandha H, Govindasami K, Muir K, Easton DF, Eeles RA, Kote-Jarai Z. Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array. British Journal of Cancer. (2016);1148:945-952. PMID: 2696403

Srinivasan S, Clements JA, Batra J. Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer? Critical Reviews in Clinical Laboratory Sciences. (2016);531:29-39. PMID: 26398894

Masso M, Allingham SF, Johnson CE, Pidgeon T, Yates P, Currow D, Eagar K.  Palliative care problem severity score:  reliability and acceptability in a national study.  Palliative Medicine (2016);30(5):479-485. PMID: 26503920

Chan R, Geary A, Yates P, Nasato G.  Editorial. Building capacity for cancer nursing research and evidence-based practice: the cancer nursing professorial precinct initiative. Asia Pacific Journal of Oncology Nursing. (2016) 3(1):28-29.

Yates P.  Editorial.  Innovative and pragmatic research designs are critical to advance nursing science.  Cancer Nursing. (2016) 39(3):251. PMID: 27081921

Ekstrom M, Allingham SF, Eagar K, Yates P, Johnson C, Currow D. Breathlessness during the last week of life in palliative care:  An Australian prospective, longitudinal study.  Journal of Pain and Symptom Management (2016);51(5):816-823. PMID: 26802626

Seim I, Jeffery PL, Thomas PB, Walpole CM, Maugham M, Fung JNT, Yap P-Y, O’Keefe AJ, Lai J, Whiteside EJ, Herington AC, Chopin LK. Multi-species sequence comparison reveals conservation of preproghrelin splice variants and a novel variant encoding a truncated ghrelin peptide. Endocrine. (2016);52:609–617. PMID: 26792793

 An J, Lai J, Zeng L, Nelson CC. “Analysis of Differential Gene Expression Based on Bayesian Estimation of Variance” in Hot Topic Issue “Nonlinear Science And Network Methods For Prediction Problems In Bioinformatics And Systems Biology” Current Bioinformatics 2016 11(2): 164-168.

2015

Liberio MS, Sadowski MC, Davis RA, Rockstroh A, Vasireddy R, Lehman ML, Nelson CC. The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cells. Oncotarget. (2015 Dec 22);6(41):43944-63. PMID: 26733491.

Ching RHH, Lau EYT, Lo J, Ling MT, Lee J, Ma MKF, Cheng BYL, Ng I and Lee TKW. Phosphorylation of Nucleophosmin at Threonine 234/237 is associated with HCC metastasis. Oncotarget. (2015 Dec 22);6(41):43483-95. PMID: 26536659

Leverier C, Sadowski M, Nelson C, Davis R. Cytotoxic C20 Diterpenoid Alkaloids from the Australian Endemic Rainforest Plant Anopterus macleayanus, J. Nat. Prod. 2015 Dec24;78(12):2908-16. doi: 10.1021/acs.jnatprod.5b00509; PMID: 26600001

Berner A, Henkel J, Woodruff MA, Saifzadeh S, Kirby G, Zaiss S, Gohlke J, Reichert JC, Nerlich M, Schuetz MA, Hutmacher DW. Scaffold-cell bone engineering in a validated preclinical animal model: Precursors vs differentiated cell source. Journal of Tissue Engineering and Regenerative Medicine.  (2015 Dec 9). PMID: 26648044

Lai J, An J, Seim I, Walpole C, Hoffman A, Moya L, Srinivasan S, Perry-Keene JL, Australian Prostate Cancer Bioresource, Wang C, Lehman ML, Nelson CC, Clements JA, Batra J,  Fusion transcript loci share many genomic features with non-fusion loci. BMC Genomics. 2015 Dec 4; 16:1021. doi:10.1186/s12864-015-2235-4. PMID: 26626734

Hutmacher DW, Holzapfel BM, De-Juan-Pardo EM, Pereira BA, Ellem SJ, Loessner D, Risbridger GP. Convergence of regenerative medicine and synthetic biology to develop standardized and validated models of human diseases with clinical relevance. Current Opinion in Biotechnology 2015 Dec; 35:127-32. doi: 10.1016/j.copbio.2015.06.001; PMID: 26121082

Osiecki MJ, Michl TD, Babur BK, Kabiri M, Atkinson K, Lott WB, Griesser HJ, Doran, MR. Packed bed bioreactor for the isolation and expansion of placental-derived mesenchymal stromal cells. PLoS ONE, (2015 Dec);10(12):e0144941. PMID: 26536659

Böttcher R, Henderson DJ, Dulla K, van Strijp D, Waanders LF, Tevz G, Lehman ML, Merkle D, van Leenders GJ, Baillie GS, Jenster G, Houslay MD, Hoffmann R. Human phosphodiesterase 4D7 (PDE4D7) expression is increased in TMPRSS2-ERG-positive primary prostate cancer and independently adds to a reduced risk of post-surgical disease progression. British Journal of Cancer. (2015 Nov 17);113(10):1502-11. PMID: 26575822

English A, Azeem A, Spanoudes K, Jones E, Tripathi B, Basu N, McNamara K, Tofail SAM, Rooney N, Riley G, ORiordan A, Cross G, Hutmacher D, Biggs M, Pandit A, Zeugolis DI. Substrate topography: A valuable in vitro tool, but a clinical red herring for in vivo tenogenesis. Acta Biomaterialia. (2015 Nov);27:3-12. PMID: 26318365

Bas O, De-Juan-Pardo EM, Chhaya MP, Wunner FM, Jeon JE, Klein TJ, Hutmacher DW. Enhancing structural integrity of hydrogels by using highly organised melt electrospun fibre constructs. European Polymer Journal. (2015 Nov);72:451-463

Sellers TA, Lim H-Y, Slavov C, Kaneva RP, Mitev VI, Spurdle A, Teixeira MR, Paulo P, Maia S, Pandha H, Michael A, Kierzek A, Batra J, Clements JA, Albanes D, Andriole GL, Berndt SI, Chanock S, Gapstur SM, Giovannucci EL, Hunter DJ, Kraft P, Le Marchand L, Ma J, Mondul AM, Penney KL, Stampfer MJ, Stevens VL, Weinstein SJ, Trichopoulou A, Bueno-De-mesquita BH, Tjønneland A, Cox DG, Maehle L, Schleutker J, Lindstrom S, Wiklund F. Genome-wide association study of prostate cancer-specific survival. Cancer Epidemiology Biomarkers and Prevention, (2015 Nov);24(11):1796-1800. PMID: 26307654

Szulkin R, Whitington T, Eklund M, Aly M, Eeles RA, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Southey MC, Fitzgerald LM, Henderson Khamenehfar A, Beischlag TV, Russell PJ, Ling MTP, Nelson C, Li PCH. Label-free isolation of a prostate cancer cell among blood cells and the single-cell measurement of drug accumulation using an integrated microfluidic chip. Biomicrofluidics. (2015 Nov 12);9(6):064104. PMID: 26594265

Gasch C, Plummer PN, Jovanovic L, McInnes L, Wescott D,  Saunders C, Nelson C, Spring K, Riethdorf S, Thomson EW, Pantel K, Mellick AS. Heterogeneity of miR-10b expression in circulating tumor cells, Scientific Reports, 2015 Nov 2; 5:15980. doi: 10.1038/srep15980; PMID: 26522916

Soekmadji C, Nelson CC. The Emerging Role of Extracellular Vesicle-Mediated Drug Resistance in Cancers: Implications in Advanced Prostate Cancer. BioMed Research International. 2015 Oct; 2015:13: 454837  doi: 10.1155/2015/454837; PMID:  26587537

Touma C, Paquet N, Richard DJ, Gamsjaeger R, Cubeddu L. hSSB1 is involved in the cellular response to oxidative DNA damage. The 29th Annual Symposium of The Protein Society. Protein Science. (2015 Oct);24(S1, SI):20

Rhee H, Gunter J, Jovanovic L, Wlliams E, Hollier B, Vela I, Wood S, Ho K, Nelson C. Update on Androgen Deprivation Therapy and Adjuvant Metformin (ADMET) trial for men with treatment naïve metastatic prostate cancer, 35th congress of the Société International d'Urologie (SIU), Melbourne, World Journal of Urology (2015 Oct);33(S1):57.

Rhee H, Gunter J, Jovanovic L, Williams E, Hollier B, Nelson C, Vela I. The use of Circulating Tumour Cells in delivery of precision medicine. Société International d'Urologie (SIU), Melbourne, World Journal of Urology (2015 Oct);33 (S1):14.

Al Olama AA, Dadaev T, Hazelett DJ, Li QY, Leongamornlert D, Saunders EJ, Stephens S, Cieza-Borrella C, Whitmore I, Garcia SB, Giles GG, Southey MC, Fitzgerald L, Gronberg H, Wiklund F, Aly M, Henderson BE, Schumacher F, Haiman CA, Schleutker J, Wahlfors T, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Brenner H, Butterbach K, Arndt V, Park JY, Sellers T, Lin HY, Slavov C, Kaneva R, Mitev V, Batra J, Clements JA, Spurdle A, Teixeira MR, Paulo P, Maia S, Pandha H, Michael A, Kierzek A, Govindasami K, Guy M, Lophatonanon A, Muir K, Vinuela A, Brown AA, Freedman M, Conti DV, Easton D, Coetzee GA, Eeles RA, Kote-Jarai Z, Consortium P, GAME-O C-CG-EP, Australian Prostate Cancer BioResource, Col UKGPCS, Collaborators UKPS. Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans. Human Molecular Genetics. (2015 Oct 1);24(19):5589-5602. PMID: 26025378

Kanagarajah A, Rhee H, Vela I, Lawson M, Preston J, Chung E, Heathcote P, Wood S. The Use of 68 Gallium(GA) Prostate Specific Membrane Antigen (PSMA) binding ligand Positron Emission Tomography (PET) and change in clinical management of patients with prostate cancer, Société International d'Urologie (SIU), Melbourne  World, Journal of Urology, (2015 Oct); 33 (S1):13.

Paquet N, Adams MN, Leong V, Ashton NW, Touma C, Gamsjaeger R, Cubeddu L, Beard S, Burgess JT, Bolderson E, O'Byrne KJ, Richard, DJ. hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway. Nucleic Acids Research (2015 Oct);43(18):8817-8829 PMID: 26261212

Fuchs AV, Tse BW, Pearce AK, Yeh MC, Fletcher NL, Huang SS, Heston WD, Whittaker AK, Russell PJ, Thurecht KJ. Evaluation of Polymeric Nanomedicines Targeted to PSMA: Effect of Ligand on Targeting Efficiency. Biomacromolecules. (2015 Oct 12);16(10):3235-47. PMID: 26335533

English A, Azeem A, Spanoudes K, Jones E, Tripathi B, Basu N, McNamara K, Tofail SAM, Rooney N, Riley G, ORiordan A, Cross G, Hutmacher D, Biggs M, Pandit A, Zeugolis DI. Data on in vitro and in vivo cell orientation on substrates with different topographies. Data in Brief. (2015 Oct1);5:379-382. PMID: 26977425

Doll A, Clark J, Nelson C, Editorial: Biomarker and translational prostate cancer research. BioMed Research International, 2015, Article ID-309851; Biomarker and translational prostate cancer research; PMID: 25664317

Szulkin R, Whitington T, Eklund M, Aly M, Eeles RA, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, Southey MC, FitzGerald LM, Henderson BE, Schumacher F, Haiman CA, Schleutker J, Wahlfors T, Tammela TLJ, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Lubiński J, Kluźniak W, Cannon-Albright L, Brenner H, Butterbach K, Stegmaier C, Park JY, Sellers T, Lim HY, Slavov C, Kaneva R, Mitev V, Batra J, Clements JA, Spurdle A, Teixeira MR, Paulo P, Maia S, Pandha H, Michael A, Kierzek A, Gronberg H, Wiklund F. Prediction of individual genetic risk to prostate cancer using a polygenic score. Prostate 2015 Sep; 75(13):1467-74. doi: 10.1002/pros.23037; PMID: 26177737

Alexander KE, Chambers S, Spurdle AB, Batra J, Lose F, O’Mara TA, Gardiner RA, Aitken JF, Clements JA, Kedda MA, Janda M. Association between single-nucleotide polymorphisms in growth factor genes and quality of life in men with prostate cancer and the general population. Quality of Life Research 2015 Sep; 24(9):2183-93. doi: 10.1007/s11136-015-0950-6; PMID: 25724697

Babur BK, Futrega K, Lott WB, Klein TJ, Cooper-White J,Doran MR. High-throughput bone and cartilage micropellet manufacture, followed by assembly of micropellets into biphasic osteochondral tissue. Cell Tissue Res. 2015 Sep; 361(3):755-68. doi: 10.1007/s00441-015-2159-y, PMID: 25924853

BE, Schumacher F, Haiman CA, Schleutker J, Wahlfors T, Tammela TLJ, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Lubinski J, Kluzniak W, Cannon-Albright L, Brenner H, Butterbach K, Stegmaier C, Park JY, Sellers T, Lim HY, Slavov C, Kaneva R, Mitev V, Batra J, Clements JA, Spurdle A, Teixeira MR, Paulo P, Maia S, Pandha H, Michael A, Kierzek A, Gronberg H, Wiklund F, Australian Prostate Cancer BioResource, PRACTICAL Consortium. Prediction of individual genetic risk to prostate cancer using a polygenic score. Prostate. (2015 Sep 15);75(13):1467-1474. PMID: 26177737

Alexander KE, Chambers S, Spurdle AB, Batra J, Lose F, O’Mara TA, Gardiner RA, Aitken JF, Clements JA, Kedda MA, Janda M. Association between single-nucleotide polymorphisms in growth factor genes and quality of life in men with prostate cancer and the general population. Quality of Life Research (2015 Sep);24(9):2183-93. PMID: 25724697

Cipitria A, Wagermaier W, Zaslansky P, Schell H, Reichert JC, Fratzl P, Hutmacher DW, Duda GN. BMP delivery complements the guiding effect of scaffold architecture without altering bone microstructure in critical-sized long bone defects: A multiscale analysis. Acta Biomaterialia. (2015 Sep);23:282-294. PMID: 26004222

Campbell A, Owen R, Brown E, Pryor D, Bernard A, Lehman M. Evaluating the accuracy of the XVI dual registration tool compared with manual soft tissue matching to localise tumour volumes for post-prostatectomy patients receiving radiotherapy. J Med Imaging Radiat Oncol. 2015 Aug ;594:527-534; doi: 10.1111/1754-9485.12332; PMID: 26109083

Kryza T, Tevz G, McPherson S, Lehman M, Stephens C, Hollier B, Nelson C, Clements J. Modulation of protease expression in prostate cancer cells after androgen deprivation. British Journal of Urology International (2015 Aug);116(S1; SI):37. PMID: 26250589

Tse BWC, Fuchs AV, Huang SS, Heston WDW, Yeh MC, Whittaker AK, Thurecht KJ, Russell PJ. Multimodal hyperbranched polymers targeting prostate specific membrane antigen (PSMA) for imaging of prostate cancer, British Journal of Urology International (2015 Aug);116(S1; SI):34. PMID: 26250589

Panchadsaram J, Tevz G, Stylianou N, Hollier B, Nelson CC, Clements J, Batra J. A multiple nucleotide length polymorphism (MNLP) mediates androgen regulation of IRX4 in prostate cancer. British Journal of Urology International (2015 Aug);116(S1; SI):36. PMID: 26250589

Hollier BG, Stylianou N, Jovanovic L, Wang C, Lehman ML, Sadowski MC, Williams E, Gunter J, Nelson CCThe mesenchymal-to-epithelial reverting transition is enriched in metastatic castration resistant prostate cancer and correlates with poor survival. British Journal of Urology International (2015 Aug);116(S1; SI):32. PMID: 26250589

Fuhrman-Luck R, Kryza T, Hastie M, Stoll T, Kleifeld O, Ho B, Lehman M, Rockstroh A, Nelson CC, Gorman J, Loessner D, Clements J. Kallikrein-related peptidase 4 induces tumour microenvironment alterations that support tumour growth. British Journal of Urology International (2015 Aug);116(S1; SI):38. PMID: 26250589

Sweeney K, Stylianou N, Tevz G, Pirlo K, Upadhyaya A, Lehman M, Fazli L, Gleave M, Gunter J,  Williams ED, Nelson CC, Hollier BG. Elucidating the role of ZEB in metastatic castration resistant prostate cancer, British Journal of Urology International (2015 Aug);116(S1; SI):35. PMID: 26250589

Rhee H, Gunter J, Jovanovic L, Williams E, Hollier B, Vela I, Nelson C. Enrichment and propagation of circulating tumour cells in men with hormone naïve metastatic prostate cancer. British Journal of Urology International (2015 Aug);116(S1; SI):33. PMID: 26250589

Soekmadji C, Ruelcke J, Wang CW, Riches JD, McPherson S, Russell PJ, Hill MM, Jenster GW, Nelson CC. Extracellular vesicles mediate paracrine signalling in androgen deprived prostate cancer. British Journal of Urology International (2015 Aug);116(S1; SI):32. PMID: 26250589

Thomas PB, Walpole CM, Jeffery PL, Jovanovic L, Herington AC, Nelson CC, Whiteside EJ, Veedu RN, Seim I, Chopin LK. The ghrelin receptor antisense long non-coding RNA GHSROS in prostate cancer growth and survival, British Journal of Urology International (2015 Aug);116(S1; SI):34. PMID: 26250589

Bock N, Loessner D, Hutmacher DW, Clements JA. A 3D in vitro model reflecting the androgen deprivation state in prostate cancer bone metastasis. British Journal of Urology International (2015 Aug);116(S1; SI):38. PMID: 26250589

Walpole C, Rae F, Jovanovic L, Odorico D, McLennan E, Lawrence M, Nelson CC, Williams ED, Batra J, Clements J. Characterisation of novel primary tumour derived epithelial prostate cancer cell lines. British Journal of Urology International (2015 Aug);116(S1; SI):36. PMID: 26250589

An JY, Lai J, Wang CW, Tevz G, Lehman ML, Nelson CC, Visualization of next generation sequencing data. British Journal of Urology International (2015 Aug);116(S1; SI):35. PMID: 26250589

Holzapfel BM, Hutmacher DW, Nowlan B, Barbier V, Thibaudeau L, Theodoropoulos C, Loessner D, Hutmacher CO, Hooper JD, Clements JA, Russell PJ, Pettit AR, Winkler IG, Levesque J-P. Tissue engineered humanized bone supports human hematopoiesis in vivo. Biomaterials, (2015 Aug);61:103-114. PMID: 26001075

Chhaya MP, Poh PSP, Balmayor ER, Van Griensven M, Schantz JT, Hutmacher DW. Additive manufacturing in biomedical sciences and the need for definitions and norms. Expert Review of Medical Devices. (2015 Aug 1);12(5):537-543. PMID: 26305837

Rockstroh A, Pokorny MR, Lehman M, Walker C, Nelson CC, Y-Box Binding Protein 1 (YB-1), a key regulator of Androgen Receptor signalling. British Journal of Urology International (2015 Aug);116(S1; SI):32. PMID: 26250589

Volpert M, Tse B, Ratther E, Stylianou N, Nouri M, Roshan-Moniri M, Butler M, Caradec J, Gregory-Evans C, Lehman M, Takhar M, Erho N, Alshalafa M, Davicioni E, Jenkins R, Karnes J, Den R, Fazli L, Gleave M, Williams E, Rennie P, Buttyan R, Gunter J, Russell P, Nelson C, Hollier B. Targeting neuropilin-1 to inhibit prostate cancer metastasis and therapy resistance. British Journal of Urology International (2015 Aug);116(S1; SI):32. PMID: 26250589

 Philp LK, Gunter JH, Sadowski MC, Tevz G, Lehman M, Otvos L, Nelson CC. Leptin receptor antagonist Allo-Aca prevents migration invasion and modifies lipogenesis pathways in prostate cells. British Journal of Urology International (2015 Aug);116(S1; SI):32. PMID: 26250589

 Gunter JH, Lee W, Philp LK, Sarkar P, Hollier BG, Sadowski M, Lehman M, Nelson CC. Insulin increases apoptotic resistance in prostate cancer cells but are sensitised by metformin. British Journal of Urology International (2015 Aug);116(S1; SI):32. PMID: 26250589

Ratther E, Sweeney K, Stylianou N, Nelson CC, Williams ED, Hollier BG. Investigating the role of neuroendocrine transdifferentiation in the progression to castration resistant prostate cancer. British Journal of Urology International (2015 Aug);116(S1; SI):32. PMID: 26250589

Tevz G, Hossain AM, Bock N, Jeet V, Bathgate RA, Williams E, Lehman M, Hutmacher DW,  Wade JD, Nelson CC. Impeding the adaptive response of prostate cancer to androgen targeted therapies with relaxin receptor antagonist. British Journal of Urology International (2015 Aug);116(S1; SI):32. PMID: 26250589

Jeet V, Rockstroh A, Lehman M, Nelson CC, Investigating the role of a potential angiogenic target, YKL40, for the treatment of metastatic prostate cancer, British Journal of Urology International. (2015 Aug);116(S1, SI):33. PMID: 26250589

Wang Q, Hardie R-A, Hoy AJ, van Geldermalsen M, Gao D, Fazli L, Sadowski MC, Balaban S, Schreuder M, Otte NJ, Lehman ML, Gleave M, Nelson CC, Bailey CG, Ritchie W, Rasko JEJ, Holst J. Inhibition of ASCT2-mediated glutamine uptake blocks prostate cancer growth. British Journal of Urology International (2015 Aug);116(S1; SI):33. PMID: 26250589

Sadowski MC, Gunter JH, Gupta R, Blanksby SJ, Nelson CC. Investigation of deregulated lipid metabolism in advanced prostate cancer. British Journal of Urology International (2015 Aug);116(S1; SI):32. PMID: 26250589

Campbell A, Owen R, Brown E, Pryor D, Bernard A, Lehman M. Evaluating the accuracy of the XVI dual registration tool compared with manual soft tissue matching to localise tumour volumes for post-prostatectomy patients receiving radiotherapy. Journal of Medical Imaging and Radiation Oncology. (2015 Aug);594:527-534. PMID: 26109083 

Johnston ST, Shah ET, Chopin LK, Sean McElwain DL, Simpson MJ. Estimating cell diffusivity and cell proliferation rate by interpreting IncuCyte ZOOM™ assay data using the Fisher-Kolmogorov model. BMC Systems Biology 2015 Jul 19; 9:38. doi: 10.1186/s12918-015-0182-y, PMID: 26188761

Wang Q, Hardie RA, Hoy AJ, van Geldermalsen M, Gao D, Fazli L, Sadowski MC, Balaban S, Schreuder M, Nagarajah R, Wong JJ, Metierre C, Pinello N, Otte NJ, Lehman ML, Gleave M, Nelson CC, Bailey CG, Ritchie W, Rasko JE, Holst J. Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development. J Pathol, 2015 Jul;236(3):278-89. doi: 10.1002/path.4518. PMID: 25693838

Amin Al Olama A, Benlloch S, Antoniou AC, Giles GG, Severi G, Neal DE, Hamdy FC, Donovan JL, Muir K, Schleutker J, Henderson BE, Haiman CA, Schumacher FR, Pashayan N, Pharoah PD, Ostrander EA, Stanford JL, Batra J, Clements JA, Chambers SK, Weischer M, Nordestgaard BG, Ingles SA, Sorensen KD, Orntoft TF, Park JY, Cybulski C, Maier C, Doerk T, Dickinson JL, Cannon-Albright L, Brenner H, Rebbeck TR, Zeigler-Johnson C, Habuchi T, Thibodeau SN, Cooney KA, Chappuis PO, Hutter P, Kaneva RP, Foulkes WD, Zeegers MP, Lu YJ, Zhang HW, Stephenson R, Cox A, Southey MC, Spurdle AB, FitzGerald L, Leongamornlert D, Saunders E, Tymrakiewicz M, Guy M, Dadaev T, Little SJ, Govindasami K, Sawyer E, Wilkinson R, Herkommer K, Hopper JL, Lophatonanon A, Rinckleb AE, Kote-Jarai Z, Eeles RA, Easton DF; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators; PRACTICAL Consortium. Risk analysis of prostate cancer in PRACTICAL, a multinational consortium, using 25 known prostate cancer susceptibility loci. Cancer Epidemiology, Biomarkers & Prevention. (2015 Jul);24(7):1121-9. PMID: 25837820

Thibaudeau L, Holzapfel BM, Hutmacher DW. Humanized mice models for primary bone tumor and bone metastasis research. Cell Cycle. 2015 Jun 30;14(14):2191-2192. PMID: 26125650

Rose P, Yates P. Patients' outcomes related to person-centred nursing care in radiation oncology: A case study. European Journal of Oncology Nursing. (2015);19 (6):731-739. PMID: 26071200

Merlo G, Page K, Ratcliffe J, Halton K, Graves N. Bridging the gap: Exploring the barriers to using economic evidence in healthcare decision making and strategies for improving uptake. Applied Health Economics and Health Policy. (2015);133:303-309. PMID: 25288052

Miaskowski C, Dunn L, Ritchie C, Paul S, Cooper B, Aouizerat B, Alexander K, Skerman H, Yates P.  Latent class analysis reveals distinct subgroups of patients based on symptom occurrence and demographic and clinical characteristics.  Journal of Pain and Symptom Management (2015);50(1):28-37. PMID: 25647419

Gu W, Prasadam I, Yu M, Zhang F, Ling MT, Xiao Y, Yu C. Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway. BMC Cancer. (2015);28:609. PMID: 26315028

Russell PJ, Rudduck C, Tse BW-C, Williams ED. Raghavan D. Establishing prostate cancer patient derived xenografts: lessons learned from older studies. Prostate. 2015 May;75(6):628-36. doi: 10.1002/pros.22946.

Rhee H, Gunter JH, Heathcote P, Ho K, Stricker P, Corcoran NM, Nelson CCAdverse effects of androgen-deprivation therapy in prostate cancer and their management. BJU Int, 2015 Apr;115 Suppl 5:3-13. doi: 10.1111/bju.12964.

Kumar R, Sadowski MC, Levrier C, Nelson CC, Jones AJ, Holleran JP, Avery VM, Healy PC, Davis RADesign and Synthesis of a Screening Library Using the Natural Product Scaffold 3-Chloro-4-hydroxyphenylacetic Acid. J Nat Prod. 2015 Apr 24. doi: 10.1021/np500856u

Chambers KF, Mosaad EM, Russell PJ, Clements JA, Doran MR. Correction: 3D Cultures of Prostate Cancer Cells Cultured in a Novel High-Throughput Culture Platform Are More Resistant to Chemotherapeutics Compared to Cells Cultured in Monolayer. PLoS One. 2015 Apr 22;10(4):e0125641. doi: 10.1371/journal.pone.0125641

Stegeman S, Moya L, Selth LA, Spurdle AB, Clements JA, Batra J. A genetic variant of MDM4 influences regulation by multiple microRNAs in prostate cancer. Endocr Relat Cancer. 2015 Apr;22(2):265-76. doi: 10.1530/ERC-15-0013.

Stuchbery R, Kurganovs NJ, McCoy PJ, Nelson CC, Hayes VM, Corcoran NM, Hovens CM. Target acquired: progress and promise of targeted therapeutics in the treatment of prostate cancer. Curr Cancer Drug Targets. 2015 Apr 16. [Epub ahead of print]

Lisle JE, Mertens-Walker I, Stephens CR, Stansfield SH, Clements JA, Herington AC, Stephenson SA. Murine, but not human, ephrin-B2 can be efficiently cleaved by the serine protease kallikrein-4: implications for xenograft models of human prostate cancer. Exp Cell Res. 2015 Apr 10;333(1):136-46. doi: 10.1016/j.yexcr.2015.02.014.

Moon H, Ruelcke JE, Choi E, Sharpe LJ, Nassar ZD, Bielefeldt-Ohmann H, Parat MO, Shah A, Francois M, Inder KL, Brown AJ, Russell PJ, Parton RG, Hill MM. Diet-induced hypercholesterolemia promotes androgen independent prostate cancer metastasis via IQGAP1 and caveolin-1. Oncotarget (2015 April);6(10):7438-53. PMID: 25924234

Stegeman S, Amankwah E, Klein K, O'Mara TA, Kim D, Lin HY, Permuth-Wey J, Sellers TA, Srinivasan S, Eeles R, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pharoah P, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Kaneva R, Teixeira MR; PRACTICAL Consortium; Australian Prostate Cancer BioResource, Spurdle AB, Clements JA, Park JY, Batra J. A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer. Cancer Discov. 2015 Apr;5(4):368-79. doi: 10.1158/2159-8290.CD-14-1057.

Davies NM, Gaunt TR, Lewis SJ, Holly J, Donovan JL, Hamdy FC, Kemp JP, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H, consortium P, Lathrop M, Smith GD, Martin RM. The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium. Cancer Causes and Control. (2015);2611:1603-1616. PMID: 26387087

Doll A, Clark J, Nelson C. Editorial: Biomarker and translational prostate cancer research. BioMed Research International. (2015):309851. PMID: 25664317

Yates P, Chambers S, Mitchell G, Skerman H, Wilson A, Colquist S, Douglas C, Burge F, Gordon L, Stephenson J, Welch L, Wyld D, Hughes B.  A prospective, longitudinal study of the use of health services by advanced cancer patients:  implications for cancer nurses.  Cancer Nursing (2015)38(4S),S29.

Sykes J, Yates P, Langbecker D. Evaluation of the implementation of the prostate cancer specialist nurse role. Cancer Forum. (2015);39(3):199-203.

Mertens-Walker I, Fernandini BC, Maharaj MS, Rockstroh A, Nelson CC, Herington AC, Stephenson SA. The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of integrin-β8 in prostate cancer cells. BMC Cancer. 2015 Mar 22;15:164. doi: 10.1186/s12885-015-1164-6.

An J, Lai J, Wood DLA, Sajjanhar A, Wang C, Tevz G, Lehman ML, Nelson CC. RNASeqBrowser: A genome browser for simultaneous visualization of raw strand specific RNAseq reads and UCSC genome browser custom tracks. BMC Genomics. 2015 March 1. doi:10.1186/s12864-015-1346-2 [Epub ahead of print]

Davis ID, Long A, Yip S, Espinoza D, Thompson JF, Kichenadasse G, Harrison M, Lowentha RM, Pavlakis N, Azad A, Kannourakis G, Steer C, Goldstein D, Shapiro J, Harvie R, Jovanovic L, Hudson AL, Nelson CC,  Stockler MR, Martin A. EVERSUN: A phase 2 trial of alternating sunitinib and everolimus as first line therapy for advanced renal cell carcinoma. Ann Oncol. 2015 Feb 20. doi: 10.1093/annonc/mdv078 [Epub ahead of print]

Husaini Y, Lockwood GP, Nguyen TV, Tsai VW, Mohammad MG, Russell PJ, Brown DA, Breit SN. Macrophage inhibitory cytokine-1 (MIC-1/GDF15) gene deletion promotes cancer growth in TRAMP prostate cancer prone mice. PLoS One. 2015 Feb 19;10(2):e0115189. doi: 10.1371/journal.pone.0115189. eCollection 2015.

An J, Lai J, Zeng L, Nelson CC. Analysis of Differential Gene Expression Based on Bayesian Estimation of Variance. Current Bioinformatics Hot Topic Issue “Nonlinear Science And Network Methods For Prediction Problems In Bioinformatics And Systems Biology” 2015 Feb 9

Levrier C, Sadowski MC, Nelson CC, Healy PC, Davis RA. Denhaminols A–H, Dihydro-β-agarofurans from the Endemic Australian Rainforest Plant Denhamia celastroides. J. Nat. Prod. 2015 Jan 23;78(1):111-9. doi:10.1021/np500740f

2014

Tse BW, Jovanovic L, Nelson CC, de Souza P, Power CA, Russell PJ. From bench to bedside: immunotherapy for prostate cancer. Biomed Res Int. 2014;2014:981434. doi: 10.1155/2014/981434. Epub 2014 Sep 4.

An J, Lai JSajjanhar A, Batra J, Wang C, Nelson CC. J-Circos: An Interactive Circos plotter. Bioinformatics. 2014 Dec 24. doi:10.1093/bioinformatics/btu842

Nouri M, Ratther E, Stylianou N, Nelson CC, Hollier BG, Williams ED. Androgen-targeted therapy-induced epithelial mesenchymal plasticity and neuroendocrine transdifferentiation in prostate cancer: an opportunity for intervention. Frontiers in Oncology. 2014 Dec 23. doi: 10.3389/fonc.2014.00370

Loessner D, Holzapfel BM, Clements JA. Engineered microenvironments provide new insights into ovarian and prostate cancer progression and drug responses. Advanced Drug Delivery Reviews, 2014 Dec 15. doi:10.1016/j.addr.2014.06.001

Loh J, Jovanovic L, Lehman M, Capp A, Pryor D, Harris M, Nelson C, Martin J. Circulating tumor cell detection in high-risk non-metastatic prostate cancer.  J Cancer Res Clin Oncol. 2014 Dec; 140(12):2157-62. doi: 10.1007/s00432-014-1775-3

Tse B, Cowin GJ, Soekmadji C, Jovanovic L, Vasireddy SJ, Ling M-T, Khatri A, Liu T, Thierry B, Russell PJ. Prostate specific membrane antigen (PSMA)-targeting iron oxide magnetic nanoparticles (MNPs) enhance MRI of preclinical prostate cancer. Nanomedicine.  2014 Nov 19. doi:10.2217/nnm.14.122

Chambers KF, Mosaad EM, Russell PJ, Clements JA, Doran MR. 3D Cultures of Prostate Cancer Cells Cultured in a Novel High-Throughput Culture Platform Are More Resistant to Chemotherapeutics Compared to Cells Cultured in Monolayer PLoS One. 2014 Nov 7. doi: 10.1371/journal.pone.0111029

Liberio MS, Sadowski MC, Soekmadji C, Davis RA, Nelson CC. Differential Effects of Tissue Culture Coating Substrates on Prostate Cancer Cell Adherence, Morphology and Behavior. PLoS One. 2014 Nov 6. doi: 10.1371/journal.pone.0112122

Liberio MS, Sadowski MC, Nelson CC, Davis RA. Identification of Eusynstyelamide B as a Potent Cell Cycle Inhibitor Following the Generation and Screening of an Ascidian-Derived Extract Library Using a Real Time Cell Analyzer. Marine Drugs. 2014 October 17. doi:10.3390/md12105222

Al Olama AA, Kote-Jarai Z, Berndt SI, Conti DV, Schumacher F, Han Y, Benlloch S, Hazelett DJ, Wang Z, Saunders E, Leongamornlert D, Lindstrom S, Jugurnauth-Little S, Dadaev T, Tymrakiewicz M, O Stram D, Rand K, Wan P, Stram A, Sheng X, Pooler LC, Park K, Xia L, Tyrer J, Kolonel LN, Le Marchand L, Hoover RN, Machiela M, Yeager M, Burdette L, Chung CC, Hutchinson A, Yu K, Goh C, Ahmed M, Govindasami K, Guy M, Tammela TLJ, Auvinen A, Wahlfors T, Schleutker J, Visakorpi T, Leinonen KA, Xu J, Aly M, Donovan J, Travis RC, Key TJ, Siddiq A, Canzian F, Khaw KT, Takahashi A, Kubo M, Pharoah P, Pashayan N, Weischer M, Nordestgaard BG, Nielsen SF, Klarskov P, Røder MA, Iversen P, Thibodeau SN, McDonnell SK, Schaid DJ, Stanford JL, Kolb S, Holt S, Knudsen B, Coll AH, Gapstur SM, Diver WR, Stevens VL, Maier C, Luedeke M, Herkommer K, Rinckleb AE, Strom S, Pettaway C, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, Cannon-Albright L, Cybulski C, Wokołorczyk D, Kluźniak W, Park J, Sellers T, Lin HY, Isaacs WB, Partin AW, Brenner H, Dieffenbach AK, Stegmaier C, Chen C, Giovannucci EL, Ma J, Stampfer M,Penney KL, Mucci L, John EM, Ingles SA, Kittles RA, Murphy AB, Pandha H, Michael A, Kierzek A, Blot W, Signorello LB, Zheng W, Albanes D, Virtamo J, Weinstein S, Nemesure B, Carpten J, Leske C, Wu SY, Hennis A, Kibel AS, Rybicki BA, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA,  Zheng SL, Batra J, Clements J, Spurdle A, Teixeira MR, Paulo P, Maia S, Slavov C, Kaneva R, Mitev V, Witte JS, Casey G, Gillanders EM, Seminara D, Riboli E, Hamdy FC, Coetzee GA, Li Q, Freedman ML, David J Hunter, Kenneth Muir, Henrik Gronberg, David E Neal, Melissa Southey, Giles GG, Severi G, The Breast and Prostate Cancer Cohort Consortium (BPC3), The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium, The COGS (Collaborative Oncological Gene-environment Study) Consortium, The GAME-ON/ELLIPSE Consortium, Michael B Cook, Hidewaki Nakagawa, Fredrik Wiklund, Peter Kraft, Stephen J Chanock, Brian E Henderson, Douglas F Easton, Rosalind A Eeles, Christopher A Haiman. A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. Nature Genetics. 2014 October. doi:10.1038/ng.3094

Martin C. Sadowski, Rebecca H. Pouwer, Jennifer H. Gunter, Amy A. Lubik, Ronald J. Quinn, Colleen C. Nelson. The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer. Oncotarget. 2014 October 15;5(19):9362-81.

Jeet V, Hollier B, Tevz G, Lehman M, Nelson C. Elevated YKL40 is Associated with Advanced Prostate Cancer and Positively Regulates Invasion and Migration of Prostate Cancer Cells. Endocrine-related Cancer, 2014 Oct. doi: 10.1530/ERC-14-0267

Lai J, Batra J. Speckle-type POZ protein mutations interrupt tumor suppressor function of speckle-type POZ protein in prostate cancer by affecting androgen receptor degradation. Asian J Androl, 2014 Sept-Oct. doi: 10.4103/1008-682X.133323.

Dong Gao, Ian Vela, Andrea Sboner, Phillip J. Iaquinta, Wouter R. Karthaus, Anuradha Gopalan, Catherine Dowling, Jackline N. Wanjala, Eva A. Undvall, Vivek K. Arora, John Wongvipat, Myriam Kossai, Sinan Ramazanoglu, Luendreo P. Barboza, Wei Di, Zhen Cao, Qi Fan Zhang, Inna Sirota, Leili Ran, Theresa Y. MacDonald, Himisha Beltran, Juan-Miguel Mosquera, Karim A. Touijer, Peter T. Scardino, Vincent P. Laudone, Kristen R. Curtis, Dana E. Rathkopf, Michael J. Morris, Daniel C. Danila, Susan F. Slovin, Stephen B. Solomon, James A. Eastham, Ping Chi, Brett Carver, Mark A. Rubin, Howard I. Scher, Hans Clevers, Charles L. Sawyers, Yu Chen. Organoid Cultures Derived from Patients with Advanced Prostate Cancer. Cell. 2014 September 25. doi.org/10.1016/j.cell.2014.08.016

White-Al Habeeb NM, Ho LT, Olkhov-Mitsel E, Kron K, Pethe V, Lehman M, Jovanovic L, Fleshner N, van der Kwast T, Nelson CC, Bapat B. Integrated analysis of epigenomic and genomic changes by DNA methylation dependent mechanisms provides potential novel biomarkers for prostate cancer. Oncotarget. 2014 Sep 15;5(17):7858-69.

Clements JA, Dong Y, Harrington BS, Adams MN, Wormann A, Stephenson SA, Lisle J, Herington A, Hooper JD. Activation of membrane bound proteins and receptor systems: a link between tissue kallikrein and the KLK-related peptidases. Biol Chem. 2014 Sep. doi: 10.1515/hsz-2014-0147

Tang KD, Ling MT. Targeting drug-resistant prostate cancer with dual PI3K/mTOR inhibition. Curr Med Chem. 2014 Sep;21(26):3048-56

Lai J, An J, Nelson C, Lehman M, Batra J, Clements J. Analysis of androgen and anti-androgen regulation of KLK-related peptidase 2, 3, and 4 alternative transcripts in prostate cancer. Biol Chem. 2014 Sep;395(9):1127-32. doi: 10.1515/hsz-2014-0149.

Pearce A, Rolf B, Russell PJ, Tse B C-W, Whittaker AK, Fuchs AV, Thurecht KJ. Development of a polymer theranostic for prostate cancer. Polymer Chemistry. 2014 Sep 4. doi:10.1039/C4PY00999A

Jiyuan An, John Lai, Atul Sajjanhar, Melanie L Lehman, Colleen C Nelson. miRPlant: an integrated tool for identification of plant miRNA from RNA sequencing data. BMC Bioinformatics. 2014 Aug 12;15:275. doi: 10.1186/1471-2105-15-275.

Liu J, Lau YET, Chen J, Yong J, Tang KD, Lo J, Ng IOL, Lee TKW, Ling MT(P), Polysaccharopeptide enhanced the anti-cancer effect of gamma-tocotrienol through activation of AMPK. BMC Complement Altern Med. 2014 Aug 16;14:303. doi: 10.1186/1472-6882-14-303.

Nicole M. A. White-Al Habeeb, Linh T. Ho, Ekaterina Olkhov-Mitsel, Ken Kron, Vaijayanti Pethe, Melanie Lehman, Lidija Jovanovic, Neil Fleshner, Theodorus van der Kwast, Colleen C. Nelson, Bharati Bapat. Integrated analysis of epigenomic and genomic changes, by DNA methylation-dependent mechanisms, provides potential novel biomarkers for prostate cancer. Oncotarget. 2014 Aug 6 15;5(17):7858-69.

Kulasinghe A, Perry C, Jovanovic L, Nelson C, Punyadeera C. Circulating tumour cells in metastatic head and neck cancer. Int J Cancer. 2014 Aug 1. doi: 10.1002/ijc.29108.

Khokhar S, Feng Y, Campitelli MR, Ekins MG, Hooper JN, Beattie KD, Sadowski MC, Nelson CC, Davis RAIsolation, structure determination and cytotoxicity studies of tryptophan alkaloids from an Australian marine sponge Hyrtios sp. Bioorg Med Chem Lett. 2014 Aug. doi: 10.1016/j.bmcl.2014.05.104.

Moon H, Lee CS, Inder KL, Sharma S, Choi E, Black DM, Lê Cao KA, Winterford C, Coward JI, Ling MT, The Australian Prostate Cancer BioResource, Craik DJ, Parton RG, Russell PJ, Hill MM. (2013) PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer. Oncogene. 2014 Jul 3. doi: 10.1038/onc.2013.315.

Fuhrman-Luck RA, Munasinghage LS, Dong Y, Irving-Rodgers H, Stoll T, Hastie ML, Loessner D, Gorman JJ, Clements JA. Proteomic and other analyses to determine the functional consequences of deregulated kallikrein-related peptidase (KLK) expression in prostate and ovarian cancer. Proteomics Clinical Applications Special Issue: Proteases and Disease. 2014 Jun, 8(5-6):403-415. doi: 10.1002/prca.201300098

Holzapfel BM, Wagner F, Loessner D, Holzapfel NP, Thibaudeau L, Crawford R, Ling MT(P) Clements JA, Russell PJ, Hutmacher DW. Species-specific homing mechanisms of human prostate cancer metastasis in tissue engineered bone. Biomaterials 2014 Apr. doi: 10.1016/j.biomaterials.2014.01.062

Richie CD, Laura P, Steven CB, Skerman HM, Merriman J, Aouizerat B, Alexander K, Yates P, Cataldo J, Miaskowski C. Differences in the symptom experience of older oncology outpatients. Journal of Pain and Symptom Management, 2014 Apr;47(4):697-709. doi: 10.1016/j.jpainsymman.2013.05.017.

Tang KD, Ling MT TIE-2 regulates stemness and metastasis of prostate cancer cells. European Journal of Cancer. 2014 May. doi:10.1016/j.ejca.2014.03.040

Pokorny MR, de Rooij M, Duncand E, Schrödere FH, Parkinsonf R, Barentszb JO, Thompson LC. Prospective Study of Diagnostic Accuracy Comparing Prostate Cancer Detection by Transrectal Ultrasound–Guided Biopsy Versus Magnetic Resonance (MR) Imaging with Subsequent MR-guided Biopsy in Men Without Previous Prostate Biopsies. European Urology. 2014 Mar 14. doi:10.1016/j.eururo.2014.03.002

McCarthy AL, Cook PS, Yates P. Engineering the fitness of older patients for chemotherapy: an exploration of comprehensive geriatric assessment in practice. Health (London) 2014 Mar;18(2):196-212 doi:10.1177/1363459313488007

Batra J, Srinivasan S, Clements J, Single Nucleotide Polymorphisms (SNPs) in Yousef GM and Jothy S (Eds) Molecular Testing in Cancer. Springer Link. 2014 Mar 15. doi: 10.1007/978-1-4899-8050-2_5

Saunders EJ, Dadaev T, Leongamornlert DA, Jugurnauth-Little S, Tymrakiewicz M, Wiklund F, Al Olama AA, Benlloch S, Neal DE, Hamdy FC, Donovan JL, Giles GG, Severi G, Gronberg H, Aly M, Haiman CA, Schumacher F, Henderson BE, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock S, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Nordestgaard BG, Canzian F, Campa D, Riboli E, Key TJ, Travis RC, Ingles SA, John EM, Hayes RB, Pharoah P, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Clements JA, Teixeira MR, Xu J, Mikropoulos C, Goh C, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A; COGS-CRUK GWAS-ELLIPSE (Part of GAME-ON) Initiative; UK Genetic Prostate Cancer Study Collaborators; UK ProtecT Study Collaborators; PRACTICAL Consortium, Easton DF, Muir K, Eeles RA, Kote-Jarai Z. Fine-Mapping the HOXB Region Detects Common Variants Tagging a Rare Coding Allele: Evidence for Synthetic Association in Prostate Cancer. PLoS Genet 2014, Feb 13;10(2): e1004129 doi:10.1371/journal.pgen.1004129

Sieh S, Taubenberger AV, Lehman ML, Clements JA, Nelson CC, Hutmacher DW. Paracrine interactions between LNCaP prostate cancer cells and bioengineered bone in 3D in vitro culture reflect molecular changes during bone metastasis. Bone. 2014 Feb 12. doi: 10.1016/j.bone.2014.02.001

Saha PS, Doran M, Different in vitro activation methods for latent transforming growth factors (TGF)–β : considerable exogenous factors to promote higher mesenchymal-origin cell proliferation in a bioprocessing platform. Biomedical Science and Engineering, 2014 Feb 12: 2(1), pp. 5-12. doi: 10.12691/bse-2-1-2

Hesami P, Holzapfel BM, Taubenberger A, Roudier M, Fazli L, Sieh S, Thibaudeau L, Gregory LS, Hutmacher DW, Clements JA. A humanized tissue-engineered in vivo model to dissect interactions between human prostate cancer cells and human bone. Clin Exp Metastasis. 2014 Feb 8. doi: 10.1007/s10585-014-9638-5

Vela I, Morrissey C, Zhang X, Chen S, Corey E, Strutton GM, Nelson CC, Nicol DL, Clements JA, Gardiner EM. PITX2 and non-canonical Wnt pathway interaction in metastatic prostate cancer. Clinical and Experimental Metastasis. 2014 Feb;31(2):199-211. doi: 10.1007/s10585-013-9620-7.

Sujita D, Bradley N, Williams ED, Frauman AG. CD151 is associated with prostate cancer cell invasion and lymphangiogenesis in vivo. Oncol Rep. 2014 Jan. doi: 10.3892/or.2013.2823

2013

Cook MM, Doran MR, Kollar K, Barbier V, Winkler IG, Levesque, J-P, Brooke G, Atkinson K. Engraftment outcomes after HPC co-culture with mesenchymal stromal cells and osteoblasts. J. Clin. Med. 2013 Sep 23:2(3):115-135. doi:10.3390/jcm2030115

Wang Q, Tiffen J, Bailey CG, Lehman ML, Ritchie W, Fazli L, Metierre C, Feng YJ, Li E, Gleave M, Buchanan G, Nelson CC, Rasko JE, Holst J. Targeting Amino Acid Transport in Metastatic Castration-Resistant Prostate Cancer: Effects on Cell Cycle, Cell Growth, and Tumor Development. J Natl Cancer Inst. 2013 Oct 2. doi: 10.1093/jnci/djt241

JNCI editorial: Tee AR, Metastatic Castration-Resistant Prostate Cancer Hungers for Leucine. J Natl Cancer Inst. 2013 Oct. doi: 10.1093/jnci/djt252

ASCO Post’s Journal spotlight: Stenger M, L-Type Amino Acid Transporters (LAT) Inhibition May Be a New Therapeutic Option for Metastatic Castration-Resistant Prostate Cancer, The ASCO Post, 15 January 2014

Kabiri M, Lott WB, Kabiri E, Russell PJ, and Doran MR In vitro assessment of migratory behavior of two cell populations in a simple multichannel microdevice. Processes, 2013 Dec 18:1(3):349-359. doi:10.3390/pr1030349

Soekmadji C, Russell PJ, Nelson CC, Exosomes in Prostate Cancer: Putting together the Pieces of a Puzzle, Cancers 2013 Nov, 5(4), 1522-1544; doi:10.3390/cancers5041522

Seim I, Jeffery P, Amorim L, Whiteside E, Lourie R, Herington A, Chopin L, Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin, Reprod Biol Endocrinol. 2013 Jul 23;11:70. doi: 10.1186/1477-7827-11-70.

Lose F, Batra J, O’Mara T, Fahey P, Marquart L, Eeles RA, Easton DF, Olama AA, Zsofia K-J, Guy M, Muir K, Lophatananon A, Rahman AA, Neal DE, Hamdy FC, Donovan JL, Chambers S, Gardiner RA, Aitken JF, Yaxley J. Common variation in Kallikrein genes KLK5, KLK6, KLK12, and KLK13 and risk of prostate cancer and tumor aggressiveness. Urologic Oncology: Seminars and Original Investigations. July 2013; 31(5):635-643. doi:10.1016/j.urolonc.2011.05.011

Clark AK, Taubenberger AV, Taylor RA, Niranjan B, Chea ZY, Zotenko E, Sieh S, Pedersen JS, Norden S, Frydenberg M, Grummet JP, Pook DW; Australian Prostate Cancer BioResource, Stirzaker C, Clark SJ, Lawrence MG, Ellem SJ, Hutmacher DW, Risbridger GP. A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer. Biomaterials. 2013 Jul;34(20):4777-85. doi:10.1016/j.biomaterials.2013.03.005.

Holzapfel NP, Holzapfel BM, Champ S, Feldthusen J, Clements JA, Hutmacher DW  The potential role of lycopene for the prevention and therapy of prostate cancer: from molecular mechanisms to clinical evidence. Int. J. Mol. Sci. 2013 Jul 12:14(7):14620-14646. doi:10.3390/ijms140714620

Clements  J, Hooper J, Dong Y The human tissue kallikrein and kallikrein-related peptidase family. In Rawlings, Neil & Salvesen, Guy (Eds.) Handbook of Proteolytic Enzymes [3rd ed.]. Academic Press (Elsevier), New York & London, pp. 2747-2756.

Kwan PS, Lau CC, Chiu YT, Man C, Liu J, Tang KD, Yong CW, Ling P. Daxx regulates mitotic progression and prostate cancer predisposition. Carcinogenesis, 2013 Apr:34(4): 750-759. doi:10.1093/carcin/bgs391

Lott WB, Doran MR. Do RNA viruses require genome cyclisation for replication? Trends in Biochemical Sciences, 2013 Jul:38(7):350-355. doi:10.1016/j.tibs.2013.04.005

Yates P. Cancer. In Chang, Esther & Johnson, Amanda (Eds.) Chronic Illness and Disability: Principles for Nursing Practice [2nd ed.]. Churchill Livingstone, Elsevier, Sydney, Australia, 2013, pp. 531-545.

Yates P. Caring for the cancer survivor. In Crisp, C., Taylor, C., Douglas, C., & Rebeiro, G. (Eds.) Potter and Perry's Fundamentals of Nursing [4th ed.]. Mosby Elsevier, Chatswood, NSW, 2013:pp. 1474-1486.

Rose P, Yates P. Person centred nursing care in radiation oncology: a case study. European Journal of Oncology Nursing, 2013 Oct:17(5), pp. 554-562. doi:10.1016/j.ejon.2013.02.001

Cataldo JK, Paul S, Cooper B, Skerman HM, Alexander K, Aouizerat B, Blachman V, Merriman J, Dunn L, Ritchie C, Yates P, Miaskowski C. Differences in the symptom experience of older versus younger oncology outpatients: a cross-sectional study. BMC Cancer, 2013 Jan 3:13(6), pp. 1-16. doi:10.1186/1471-2407-13-6

Yates P, Aranda S. 40 years of cancer nursing in Australia: the emergence of a specialty. Cancer Forum, 2013:37(1), pp. 35-38.

Gunter JH, Sarkar P, Lubik A, Nelson C. (2013) New players for advanced prostate cancer and the rationalisation of insulin-sensitising medication. Int J Cell Biol. 2013 Jan. doi: 10.1155/2013/834684

Baron PS, Neve JE, Camp D, Suraweera L, Lam A, Lai J, Jovanovic L, Nelson C, Davis RA.  Design, synthesis and spectroscopic characterisation of a focused library based on the polyandrocarpamine scaffold. Magnetic Resonance in Chemistry, 2013 Jun;51(6):358-63. doi: 10.1002/mrc.3958.

Eeles RA, Olama AA, Benlloch S, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S, Dadaev T, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock SJ, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah PD, Pashayan N, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle AB, Clements JA, Teixeira MR, Dicks E, Lee A, Dunning AM, Baynes C, Conroy D, Maranian MJ, Ahmed S, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As NJ, Woodhouse CJ, Thompson A, Dudderidge T, Ogden C, Cooper CS, Lophatananon A, Cox A, Southey MC, Hopper JL, English DR, Aly M, Adolfsson J, Xu J, Zheng SL, Yeager M, Kaaks R, Diver WR, Gaudet MM, Stern MC, Corral R, Joshi AD, Shahabi A, Wahlfors T, Tammela TL, Auvinen A, Virtamo J, Klarskov P, Nordestgaard BG, Røder MA, Nielsen SF, Bojesen SE, Siddiq A, Fitzgerald LM, Kolb S, Kwon EM, Karyadi DM, Blot WJ, Zheng W, Cai Q, McDonnell SK, Rinckleb AE, Drake B, Colditz G, Wokolorczyk D, Stephenson RA, Teerlink C, Muller H, Rothenbacher D, Sellers TA, Lin HY, Slavov C, Mitev V, Lose F, Srinivasan S, Maia S, Paulo P, Lange E, Cooney KA, Antoniou AC, Vincent D, Bacot F, Tessier DC; COGS–Cancer Research UK GWAS–ELLIPSE (part of GAME-ON) Initiative; Australian Prostate Cancer Bioresource; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators; PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium, Kote-Jarai Z, Easton DF. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet. 2013 Apr;45(4):385-91, 391e1-2. doi: 10.1038/ng.2560.

Patnala R, Clements J, Batra J. Candidate gene association studies: a comprehensive guide to useful in silico tools. BMC Genetics 2013 14:39. doi: 10.1186/1471-2156-14-39.

Kote-Jarai Z, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Dadaev T, Jugurnauth-Little S, Ross-Adams H, Amin Ali AL, Benloch S, Halim S, Russel R, Ghoussaini M, Luccarini C, Dennis J, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock S, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles S, John EM, Hayes RB, Pharoah P, Pashayan N, Khaw K-T, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle A, Clements JA,  Teixeira MR, Dicks E, Lee A, Dunning AM, Baynes C, Conroy D, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan, Vincent D, Bacot, F, Tessier DC, The UK Genetic Prostate Cancer Study Collaborative/British Association of Urological Surgeons’ Secion of Oncology, The UK ProtecT Study Collaborators, The PRACTICAL Consortium, Easton DF, Eeles RA.  Fine-mapping identifies multiple prostate cancer risk loci on 5p15, one of which associates with TERT expression. Hum Mol Genet. 2013 Jun 15;22(12):2520-8. doi: 10.1093/hmg/ddt086.

Holzapfel BM, Thibaudeau L, Hesami P, Taubenberger A, Holzapfel NP, Mayer-Wagner S, Power C, Clements J, Russell P, Hutmacher DW. Humanized xenograft models of bone metastasis revisited: novel insights into species-specific mechanisms of cancer cell osteotropism. Cancer Metastasis Rev. 2013 Jun;32(1-2):129-45. doi: 10.1007/s10555-013-9437-5.

Lubik AA, Gunter JH, Hollier BG, Ettinger S, Fazli L, Stylianou N, Hendy SC, Adomat HH, Gleave ME, Pollak M, Herington A, Nelson CC. IGF2 increases de novo steroidogenesis in prostate cancer cells. Endocr Relat Cancer. 2013 Mar 22;20(2):173-86. doi: 10.1530/ERC-12-0250.

Lisle JE, Mertens-Walker I, Rutkowski R, Herington AC, Stephenson SA. Eph receptors and their ligands: promising molecular biomarkers and therapeutic targets in prostate cancer. Biochim Biophys Acta 2013 Apr; 1835(2):243-57. doi: 10.1016/j.bbcan.2013.01.003.

Kavanagh JN, Currell FJ, Timson DJ, Savage KI, Richard DJ, McMahon SJ, Hartley O, Cirrone GAP, Romano F, and Prise KM. Antiproton Induced DNA Damage: Proton Like in Flight, Carbon-Ion Like Near Rest. Scientific Reports 3:1770 (2013). doi: 10.1038/srep01770

Ashton NW, Bolderson E, Cubeddu L, O’Byrne KJ, Richard  DJ. Human single-stranded DNA binding proteins are essential for maintaining genomic stability. BMC molecular biology 14 (1), 1-20. doi: 10.1186/1471-2199-14-9.

Schrobback K, Wrobel J, Hutmacher D, Woodfield T, Tim BF, & Klein TJ. (2013) Stage-specific embryonic antigen-4 is not a marker for chondrogenic and osteogenic potential in cultured chondrocytes and mesenchymal progenitor cells. Tissue Engineering Part A, 2013 Jun;19(11&12), pp. 1316-1326. doi: 10.1089/ten.TEA.2012.0496.

Babur BK, Ghanavi P, Levett P, Lott WB, Klein T, Cooper-White J, Crawford R, Doran  MR.  The interplay between chondrocyte redifferentiation pellet size and oxygen concentration. PLoS ONE. 2013;8(3), e58865. doi: 10.1371/journal.pone.0058865.

Yao Y, Suraokar M, Darnay BG, Hollier BG, Shaiken TE, Asano T, Chen CH, Chang BHJ, Lu Y, Mills GB, Sarbassov D, Mani SA, Abbruzzese JL, Reddy SAG. (2013) BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation. Science Signalling, 6:257, ra2. doi:10.1126/scisignal.2003295

Al Olama AA, Kote-Jarai Z, Schumacher FR, Wiklund F, Berndt SI, Benlloch S, Giles GG, Severi G, Neal DE, Hamdy FC, Donovan JL, Hunter DJ, Henderson BE, Thun MJ, Gaziano M, Giovannucci EL, Siddiq A, Travis RC, Cox DG, Canzian F, Riboli E, Key TJ, Andriole G, Albanes D, Hayes RB, Schleutker J, Auvinen A, Tammela TLJ, Weischer M, Stanford JL, Ostrander EA, Cybulski C, Lubinski J, Thibodeau SN, Schaid DJ, Sorensen KD, Batra J, Clements JA,  Chambers S, Aitken J, Gardiner RA, Maier C, Vogel W, Dörk T, Brenner H, Habuchi T, Ingles S, John EM, Dickinson JL, Cannon-Albright L, Teixeira MR, Kaneva R, Zhang H-W, Lu Y-J, Park JY, Cooney KA, Muir KR, Leongamornlert DA, Saunders E, Tymrakiewicz M, Mahmud N, Guy M, Govindasami K, O’Brien LT, Wilkinson RA, Hall AL, Sawyer EJ, Dadaev T, Morrison J, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC,  Van As N, Woodhouse CJ, Thompson A, Dudderidge T, Ogden C, Cooper CS, Lophatonanon A, Southey MC, Hopper JL, English D, Virtamo J, Le Marchand L, Campa D, Kaaks R, Lindstrom S, Diver WR, Gapstur S, Yeager M, Cox A, Stern MC, Corral R, Aly M, Isaacs W, Adolfsson J, Xu J, Zheng SL, Wahlfors T, Taari K, Kujala P, Klarskov P, Nordestgaard BG, Rǿder MA, Frikke-Schmidt R, Bojesen SE, Fitzgerald LM, Kolb S, Kwon EM, Karyadi DM, Orntoft TF, Borre M, Rinckleb A, Luedeke M, Herkommer K, Meyer A, Serth J, Marthick JR, Patterson B, Wokolorczyk D, Spurdle A, Lose F, McDonnell SK, Joshi AD, Shahabi A, Pinto P, Ray JSA, Sellers TA, Lin H-Y, Stephenson RA, Teerlink C, Muller H, Rothenbacher D, Tsuchiya N, Narita S, Cao G-W, Slavov C, Mitev V, UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons’ Section of Oncology, The UK ProtecT Study Collaborators, The Australian Prostate Cancer Bioresource, The PRACTICAL Consortium, Chanock S, Gronberg H, Haiman CA, Kraft P, Easton DF, Eeles RA.(2012) A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. Human Molecular Genetics. 2013 Jan 15; 22 (2): 408-415. doi: 10.1093/hmg/dds425.

Betsou F, Gunter E, Clements J, DeSouza Y, Goddard KAB, Guadagni F, Yan W, Skubitz A, Somiari S, Yeadon T, Chuaqui R. Identification of evidence-based biospecimen quality-control tools: a report of the International Society for Biological and Environmental Repositories (ISBER) Biospecimen Science Working Group. Journal of Molecular Diagnostics. 2013 Jan; 15(1) 3-16. doi: 10.1016/j.jmoldx.2012.06.008

Seim I,  Lubik AA, Lehman ML, Tomlinson N, Whiteside  EJ, Herington AC, Nelson CC, Chopin L. Cloning of a novel insulin-regulated ghrelin transcript in prostate cancer. Journal of Molecular Endocrinology. 2013 Apr 15;50(2):179-91. doi: 10.1530/JME-12-0150.

An J, Lai J, Lehman ML, Nelson CC. MiRDeep*: An Integrated Application Tool For MiRNA Identification From RNA Sequencing Data. Nucleic Acids Research.  2013 Jan;41(2):727-37. doi: 10.1093/nar/gks1187.

Lubik AA, Gunter JH, Ettinger S,  Fazil L, Stylianou N, Hendy SC, Adomat HH, Hollier BG, Gleave ME, Pollak M, Herington A, Nelson CC. Insulin-like Growth Factor 2 increases de novo steroidogenesis in prostate cancer cells. Endocrine-Related Cancer, 2013 Mar 22;20(2):173-86. doi: 10.1530/ERC-12-0250.

Dalton PD, Vaquette C, Farrugia B, Dargaville TR, Brown TD, Hutmacher D Electrospinning and additive manufacturing: converging technologies. Biomaterials Science, 1, pp. 171-185. doi:10.1039/C2BM00039C

Wang C, Wu R, Yang G, Blackwood KA, Friis T, Hutmacher DW, Woodruff MA. Effect of a novel compound from Lycopodium obscurum L. on osteogenic activity of osteoblasts in vitro. Natural Science, 5(1), pp. 84-92. doi:10.4236/ns.2013.51014

An J, Lai J, Lehman ML, Nelson CC. miRDeep*: an integrated application tool for miRNA identification from RNA sequencing data. Nucleic Acids Res.2013 Jan;41(2):727-37. doi: 10.1093/nar/gks1187.

Jiyuan An, John Lai, Melanie Lehman, Colleen Nelson. MiRDeep*: An Integrated Application Tool For MiRNA Identification From RNA Sequencing Data. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Jyotsna Batra, Srilakshmi Srinivasan, Felicity Lose, Zsofia Kote-Jarai, Doug Easton, R.A. Eeles, PRACTICAL consortium, The Australian Prostate Cancer Bioresource, Amanda Spurdle, Judith Clements. Association and functional analysis of Kallikrein genetic variants with prostate cancer. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Karen Chambers, Michael Doran, Pamela Russell, Judith Clements. Culturing prostate cells as 3D micro-aggregates for drug testing. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

R. Fuhrman-Luck, M. Hastie, S. Stansfield, T. Stoll, A. Rockstroh, M. Lehman, C. Nelson, D. Loessner, J. Gorman, J. Clements. Kallikrein-related peptidase 4 initiates tumour-stroma cross-talk in prostate cancer. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Katarzyna Futrega, Karen Chambers, Bill Lott, Judith Clements, Pamela Russell, Michael Doran. High-throughput 3D tissue culture for prostate cancer drug screening. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Katarzyna Futrega, Karen Chambers, Judith Clements, Pamela Russell, Michael Doran. Engineering a High-Throughput Prostate Cancer Stem Cell Niche Mimic. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Jennifer Gunter, Amy Lubik, Raja Vasireddy, Nataly Stylianou, Stephen Hendy, Brett Hollier, Martin Gleave, Michael Pollak, Adrian Herington, Colleen Nelson. Metformin modulates key insulin-induced survival pathways in prostate cancer cells. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Varinder Jeet, Colleen Nelson. YKL40 as a therapeutic target for the treatment of metastatic Prostate Cancer. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Lidija Jovanovic, Mackenzie Mills, Allison Eckert, Simon Wood, Margot Lehman, Elizabeth McCaffrey, Irina Oleinikova, Colleen Nelson. Use of the CellSearch® Platform in Enumeration and Profiling of Circulating Tumour Cells. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

John Lai, Jiyuan An, Colleen C Nelson, Zsofia Kote-Jarai, Douglous Easton, Ali Amin, Rosalind A. Eeles on behalf of PRACTICAL consortium, Judith A Clements, Jyotsna Batra Genome-wide analyses reveal specific functional repetitive DNA that are proximal to prostate cancer risk alleles. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Melanie L. Lehman, Chenwei Wang, Gregor Tevz, Jiyuan An, John Lai, Stephen C. Hendy, Stephen McPherson, Martin Sadowski, Colleen C. Nelson. Identification of novel androgen and antiandrogen regulated long noncoding RNAs and protein-coding RNAs in prostate cancer. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Patrick Ling, Pak Shing Kwan. Daxx regulates mitotic progression and prostate cancer predisposition’. BJUI, 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Jessica Lisle, Inga Mertens-Walker, Carson Stephens, Scott Stansfield, Adrian Herington, Judith Clements, Sally-Anne Stephenson. Do proteases regulate EphB4 in prostate cancer? BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Amy Lubik, Raja Vasireddy, Jennifer Gunter, Susan Ettinger, Stephen Hendy, Michelle Hill, Martin Gleave, Michael Pollak, Adrian Herington, Colleen Nelson. Simvastatin Suppresses Insulin induced Steroidogenesis and Fatty acid Synthesis in Prostate Cancer. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Colleen Nelson, Amy Lubik, Jennifer Gunter, Melanie Lehman, Carolina Soekmadji, Chenwei Wang, Martin Gleave, Stephen Finn, Michael Pollak, Adrian Herington. Insulin Stimulates Fatty Acid Synthesis and Metabolism in Androgen Deprived Human Prostate Cancer Cell Lines. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Martin Sadowski, Rebecca Pouwer, Amy Lubik, Stephen McPherson, Colleen Nelson. Evaluation of the fatty acid synthase inhibitor triclosan in prostate cancer cells. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Phoebe Sarkar, Jennifer Gunter, Amy Lubik, Nataly Stylianou, Brett Hollier, Michael Pollak, Colleen Nelson. Insulin increases migration and invasion in androgen deprived prostate cancer cells. BJUI, 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Carolina Soekmadji, Pamela J Russell, Michelle Hill, Jonathan C Dunne, T William Jordan, Colleen Nelson. Androgen Influence on Prostate Cancer Exosomes Production and Content. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Sri Srilakshmi, Carson Stephens, Amanda Spurdle, Judith Clements, Jyotsna Batra. Functional validation of a KLK3 variant, rs17632542, with prostate cancer risk. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Stephenson SA,  Mertens-Walker I, Lisle J, William Nyberg, Carson Stephens, Leslie Burke, Raphael Rutkowski, Adrian Herington. Nuclear localization of the receptor tyrosine kinase EphB4 in prostate cancer cells. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Stylianou N,  Kashyap A, Jovanovic L, Lehman M, Wang C Gunter J, Nelson C, Hollier B. Investigating the Epithelial to Mesenchymal Transition in Prostate Cancer Invasion and Metastasis. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Tang K, Ling P. Inactivation of ATM/ATR DNA damage checkpoint promotes androgen induced chromosomal instability in prostate epithelial cells. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Tevz G, Lehman M, Lai J, An J, Wang C, Hendy SC, Nelson CC. Androgen responsive non-coding RNA regulates the expression of prostate cancer associated CTBP1 in LNCaP. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Tse B, Cowin G, Soekmadji C, Jovanovic L, Thierry B, Russell P. Application of PSMA-targeting magnetic nanoparticles into MRI of prostate cancer. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Wang C, Taciroglu A, Maetschke S, Nelson C, Ragan MA, Davis M. mCOPA: analysis of heterogeneous features in cancer expression data. BJUI, Special Issue. 2013 Aug; 112 S1:30-53. doi: 10.1111/bju.12293

Lehman M, Nelson C. Toward revealing the complexity of androgen responsive protein and non-coding transcripts in prostate cancer. In Wang, Zhou (Ed.) Androgen-Responsive Genes in Prostate Cancer : Regulation, Function and Clinical Applications. Springer 2013 Jan 28 pp. 117-134. doi:10.1007/978-1-4614-6182-1_8

2012

Reichart JC, Cipitria A, Epari DR, Saifzadeh S, Krishnakanth P, Berner A, Woodruff MA, Schell H, Mehta M, Schuetz M, Duda GN, Hutmacher DW. Porous scaffold architecture guides tissue formation. J Bone Miner Res, 2012 Jun; 27(6), pp. 1275-1288. doi: 10.1002/jbmr.1589.

Sanchez WJ, de Veer SJ, Reid JC, Sedberg JE, Hammond GL, Simmer JP, Hooper JD, Walsh TP, Clements JA and Harris JM. Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells.  Endocrinology. 2012 Jul; 153(7):3179-89. doi: 10.1210/en.2012-1011

Lawrence MG, Stephens CR, Need EF, Lai J, Buchanan G, Clements JA. Long terminal repeats act as androgen-responsive enhancers for the PSA-kallikrein locus. Endocrinology. 2012 Jul; 153(7):3199-210. doi: 10.1210/en.2012-1267.

Thompson VC, Day TK, Bianco-Miotto T, Selth LA, Guangzhou H, Thomas M, Buchanan G, Scher HI, Nelson CC, the Australian Prostate Cancer BioResource, Greenberg NM, Butler LM, Tilley W. A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease. Int J Cancer. 2012 Aug 1; 131(3):662-672. doi: 10.1002/ijc.26414

An J, Wee-Chung Liew A, Nelson CC. Seed-based biclustering of gene expression data. PLoS One. 2012 Aug 3; 7(8): e42431. doi:10.1371/journal.pone.0042431.

Husaini Y, Qiu MR, Lockwood GP, Luo XW, Shang P, Kuffner T, Tsai VW, Jiang L, Russell PJ, Brown DA, Breit SN. Macrophage inhibitory cytokine-1 (MIC-1/GDF15) slows cancer development but increases metastases in TRAMP prostate cancer prone mice. PLoS ONE. 2012 Aug 27; 7(8): e43833. doi:10.1371/journal.pone.0043833.

Rutkowski R, Mertens-Walker I, Lisle JE, Herington AC, Stephenson SA. Evidence for a dual function of EphB4 as a tumour promotor and suppressor regulated by the absence or presence of the ephrinB2 ligand. Int J Cancer. 2012 Sep 1; 131(5):E614-24. doi: 10.1002/ijcPMID: 22161689.

Sieh S, Taubenberger AV, Rizzi SC, Sadowski M, Lehman ML, Rockstroh A, An J, Clements JA, Nelson CC, Hutmacher DW. Phenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironment. PLoS ONE. 2012 Sep 5; 7(9):e40217, doi: 10.1371/journal.pone.0040217.

Uemura H, Nelson C, Schalken JA, Klotz L. Personalized Cancer Therapy for Urological Cancers: From Bench to Bedside and Back. Advances in Urology. 2012 Sep 12; Article ID 298105, 2 pages. doi:10.1155/2012/298105.

Wagholikar A, Fung M, Nelson C. Improving self-care of patients with chronic disease using online personal health record. The Australasian Medical Journal. 2012 Sep 30; 5(9):517-521.

Chopin LK, Seim I, Walpole CM, Herington AC. The ghrelin axis--does it have an appetite for cancer progression? Endocr Rev. Dec 2012; 33(6):849-91. doi: 10.1210/er.2011-1007.  

Wang C, Taciroglu A, Maetschke SR, Nelson CC, Ragan MA, Davis MJ. mCOPA: analysis of heterogeneous features in cancer expression data. Journal of Clinical Bioinformatics. 2012, 2:22 doi:10.1186/2043-9113-2-22.

Tse BWC, Scott KF, Russell PJ. Paradoxical roles of tumour necrosis factor-alpha in prostate cancer biology. Prostate Cancer. Volume 2012, Article ID 128965,  doi:10.1155/2012/128965.

Batra J, O’Mara T, Patnala R, Lose F, Clements J. Genetic polymorphisms in the human tissue kallikrein (KLK) locus and their implication in various malignant and non-malignant diseases. Biological Chemistry. Nov 2012; 393(12):1365-1390 doi:10.1515/hsz-2012-0211

Gunter JH, Lubik AA, McKenzie I, Pollak M, Nelson CC The interactions between insulin and androgens in progression to castrate resistant prostate cancer. Advances in Urology. 2012; 2012:248607. doi: 10.1155/2012/248607.

You JJ, Madigan M, Rowe A, Sajinovic M, Russell PJ, Jackson P. An inverse relationship between KAI1 expression, invasive ability and MMP-2 expression and activity in bladder cancer cell lines. Urol Oncol. 2012 Jul-Aug;30(4):502-8. doi: 10.1016/j.urolonc.2010.02.013.

Jeet V, Russell PJ, Verma N, Khatri A. Targeting aurora kinases: a novel approach to curb the growth and chemoresistance of androgen refractory prostate cancer. Cancer Drug Targets. 2012 Feb;12(2):144-163.

Wilkinson R, Woods K, D’Rozario R, Prue R, Vari F, Hardy MY, Dong Y, Clements JA, Hart DNJ, Radford KJ. Human Kallikrein 4 signal peptide induces cytotoxic T cell responses in healthy donors and prostate cancer patients. Cancer Immunology Immunotherapy. 2012 Feb;61(2):169-79. doi: 10.1007/s00262-011-1095-2

Inder KL, Zheng YZ, Davis M, Moon H, Loo D, Nguyen H, Clements J, Parton RG, Foster LJ, Hill MM. Expression of PTRF in PC3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways. Molecular & Cellular Proteomics. 2012 Feb;11(2):M111.012245. doi: 10.1074/mcp.M111.012245.

Ling MT, Luk SU, Ai-Ejeh F, Khanna KK. Tocotrienol as potential anticancer agent.  Carcinogenesis. 2012 Feb;33(2):233-9. doi: 10.1093/carcin/bgr261.

Lose F, Lawrence MG, Srinivasan S, O’Mara T, Marquart L, Chambers S, Gardiner RA, Aitken JF, Spurdle AB, Batra J, Clements JA, the Australian Prostate Cancer BioResource. Kallikrein 14 is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness. Biol Chem, 4th International Kallikrein Symposium Special Issue. 2012 Apr 1;393:403-412. doi: 10.1515/hsz-2011-0268. doi: 10.1007/s00394-011-0217-0.

Xiao J, Liong EC, Ling MT, Ching YP, Fung ML, Tipoe GL. S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice. European Journal of Nutrition. 2012 Apr;51(3):323-33. doi: 10.1007/s00394-011-0217-0.

Jang Y, Soekmadji C, Mitchell JM, Thomas WG, Thorn P. Real-Time measurement of F-Actin remodelling during exocytosis using Lifeact-EGFP transgenic animals. PLoS ONE 7(7): e39815. doi: 10.1371/journal.pone.0039815.

Soekmadji C, Angkawidjaja C, Kelly LE. Ca2+ regulates the Drosophila Stoned-A and Stoned-B proteins interaction with the C2B domain of Synaptotagmin-1. PLoS ONE 2012; 7(6): e3882. doi: 10.1371/journal.pone.0038822.

Herington AC, Lobie PE.  Signal transduction mechanisms underlying growth hormone receptor action. The Open Journal Endocrinol. 2012 6 (Suppl 1:M3): 13-21.

Dong Y, Loessner D, Sieh S, Taubenberger A, Fuhrman-Luck RA, Magdolen V, Hutmacher DW, Clements JA.Cellular model systems to study the tumour biological role of kallikrein proteases in ovarian and prostate cancer.” in Kallikrein-related peptidases, (Eds: Schmitt M, Magdolen V, Sommerhoff C, Fritz H), DeGruyter, Berlin, Germany, Dec 2012 ISBN: 978-3-11-026037-3. doi:10.1515/9783110303667.83

Batra J, O’Mara T, Lose F, Clements JA. “Single nucleotide polymorphisms in the KLK locus and their implication in various diseases.” in Kallikrein-related peptidases, (Eds: Schmitt M, Magdolen V, Sommerhoff C, Fritz H), DeGruyter, Berlin, Germany, Dec 2012, ISBN: 978-3-11-026037-3. doi: 10.1515/9783110260373.31

Stephenson S, Mertens-Walker I, Herington AC. "Signaling of receptor tyrosine kinases in the nucleus."  in Current Frontiers and Perspectives in Cell Biology, S. Najman ed. InTech, April 25, 2012, ISBN 978-953-51-0544-2, doi: 10.5772/36023.

Lehman ML, Nelson CC. "Toward revealing the complexity of androgen responsive protein and non-coding transcripts in prostate cancer." in Androgen-Responsive Genes in Prostate Cancer, Zhou Wang, Springer Science. 2012 Jan 28. ISBN 978-1-4614-6181-4. doi: 10.1007/978-1-4614-6182-1_8

Jingjing Y, Cozzi P,  Fitzgerald A, Walsh B, Russell PJ, Willcox M, Graham P, Li Y. "Prostate Cancer Biomarkers and the Emerging Proteomic Techniques Used in Biomarker Research." in Horizons in Cancer Research, Volume 47, Editor:  Watanabe HS, ISBN 978-1-61470-444-7.

2011

Lubik AA, Gunter JH, Hendy SC, Locke JA, Adomat HA, Thompson V, Herington A, Gleave ME, Pollak M, Nelson CCInsulin increases steroidogenesis in LNCaP prostate cancer cells. Cancer Research. 2011 Sept 1;71:5754-64. doi: 10.1158/0008-5472.CAN-10-2470.

Wang Q, Bailey CG, Ng C, Tiffen J, Thoeng A, Minhas V, Lehman ML, Hendy SC, Buchanan G, Nelson CC, Rasko JEJ, Holst J. Androgen receptor and nutrient signalling pathways coordinate the demand for increased amino acid transport in prostate cancer progression. Cancer Research. 2011 Dec 15;71(24):7525-36. doi: 10.1158/0008-5472.CAN-11-1821

Shiota M, Zoubeidi A, Kumano M, Beraldi E, Naito S, Nelson CC, Sorensen PHB, Gleave ME. Clusterin is a critical downstream mediator of stress-induced YB-1 transactivation in prostate cancer. Mol Cancer Res. 2011 Dec;9(12):1755-66. doi: 10.1158/1541-7786.MCR-11-0379.

Kote-Jarai Z, Olama AA, Giles GG, Severi G, Schleutker J, Weischer M, Campa D, Riboli E, Key T, Gronberg H, Hunter DJ, Kraft P, Thun MJ, Ingles S, Chanock S, Albanes D, Hayes RB, Neal DE, Hamdy FC, Donovan JL, Pharoah P, Schumacher F, Henderson BE, Stanford JL, Ostrander EA, Sorensen KD, Dörk T, Andriole G, Dickinson JL, Cybulski C, Lubinski J, Spurdle A, Clements JA, Chambers S, Aitken J, Gardiner RA, Thibodeau SN, Schaid D, John EM, Maier C, Vogel W, Cooney KA, Park JY, Cannon-Albright L, Brenner H, Habuchi T, Zhang HW, Lu YJ, Kaneva R, Muir K, Benlloch S, Leongamornlert DA, Saunders EJ, Tymrakiewicz M, Mahmud N, Guy M, O'Brien LT, Wilkinson RA, Hall AL, Sawyer EJ, Dadaev T, Morrison J, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As N, Woodhouse CJ, Thompson A, Christmas T, Ogden C, Cooper CS, Lophatonanon A, Southey MC, Hopper JL, English DR, Wahlfors T, Tammela TL, Klarskov P, Nordestgaard BG, Røder MA, Tybjærg-Hansen A, Bojesen SE, Travis R, Canzian F, Kaaks R, Wiklund F, Aly M, Lindstrom S, Diver WR, Gapstur S, Stern MC, Corral R, Virtamo J, Cox A, Haiman CA, Le Marchand L, Fitzgerald L, Kolb S, Kwon EM, Karyadi DM, Orntoft TF, Borre M, Meyer A, Serth J, Yeager M, Berndt SI, Marthick JR, Patterson B, Wokolorczyk D, Batra J, Lose F, McDonnell SK, Joshi AD, Shahabi A, Rinckleb AE, Ray A, Sellers TA, Lin HY, Stephenson RA, Farnham J, Muller H, Rothenbacher D, Tsuchiya N, Narita S, Cao GW, Slavov C, Mitev V, Easton DF, Eeles RA; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators, The Australian Prostate Cancer BioResource; PRACTICAL Consortium. Seven novel prostate cancer susceptibility loci identified by multi-stage genome-wide association study. Nature Genetics. 2011 July 10; 43:785-91. doi: 10.1038/ng.882.

Batra J,  Lose, F, Chambers S, Gardiner RA, Aitken JA, Yaxley J, Clements JA, Spurdle AB, and the Australian Prostate Cancer BioResourceA replication study examining novel common single nucleotide polymorphisms identified through a prostate cancer genome-wide association study in a Japanese population. Am J Epidemiology. 2011 Dec 15.; 174:1391-1395. doi: 10.1038/ng.882.

Batra J,  Lose, F, O’Mara T, Marquat L, Stephens C, Alexander K, Srinivasan S, Eeles RA, Easton DF, Amin Al Olama A, Kote-Jarai Z, Guy M, Muir K, Lophatananon, Rahman AA, Neal DE, Hamdy FC, Donovan JL, Chambers S, Gardiner RA, Aitken JA, Yaxley J, Kedda M-A, Clements JA, Spurdle AB. Association between Prostinogen (KLK15) genetic variants and prostate cancer risk and aggressiveness in Australia and a meta-analysis of GWAS data.  PLoS ONE. 2011; 6(11): e26527. doi: 10.1371/journal.pone.0026527

Singh P, Joshi S, Russell PJ, Khatri A. Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: A tangible union  against chemoresistant cancer. BMC Cancer. 2011 Aug 24; 11:368-383. (IF 3.15) doi: 10.1186/1471-2407-11-368.

Tse BW-C, Russell PJ, Lochner M, Förster I, Power CA. IL-18 inhibits growth of murine orthotopic prostate carcinomas via both adaptive and innate immune mechanisms. PLos ONE. 2011; 6(9):e24241. doi: 10.1371/journal.pone.0024241

Luk SU, Lee TKW, Liu J, Lee DTW, Chiu YT, Ma S, Ng IOL, Wong YC, Chan FL and Ling MT. Chemopreventive effect of PSP through targeting of prostate cancer stem cell-like population. PLoS One. 2011; 6(5):e19804. doi: 10.1371/journal.pone.0019804

Andreu-Vieyra C, Lai J, Berman BP, Frenkel B, Jia L, Jones PA, Coetzee GA. Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells. Mol Cell Biol. 2011 Dec;31(23):4648-62. doi: 10.1128/MCB.05934-11

Herington AC, Chopin LK, Jeffrey P, Veveris-Lowe T, Bui L and Clements JA. Hormone-dependent cancer: New approaches to identification of potential diagnostic and/or therapeutic biomarkers. Asia-Pacific Journal of Molecular Biology & Biotechnology 18: 61-64, 2011.

Kote-Jarai Z, Amin Al Olama A, Leongamornlert M, Tymrakiewicz M, Saunders E, Guy M, Giles GG, Severi G, Hopper JL, Sit KC, Harris JM, Batra J, Spurdle AB, Clements JA, Hamdy F, Neal D, Donovan J, Muir K, Pharoah PDP, Chanock SJ, Brown N, Castro E, Mahmud N, O’Brien L, Hall A, Sawyer E, Wilkinson R, Easton DF, Eeles RA. Identification of a novel prostate cancer susceptibility variant in the KLK3 gene. Human Genetics. 2011 Jun; 129:687-94, 2011. doi: 10.1007/s00439-011-0981-1.

Lawrence M, Margaryan N, Loessner D, Colins A, Kerr K, Turner M, Seftor E, Stephens C, Lai J, Postovit L-M, Clements J, Hendrix M. Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells. The Prostate. 2011 Aug 1; 71:1198-209, 2011. doi: 10.1002/pros.21335.

Talukdar S, Mandal M, Hutmacher D, Russell PJ, Soekmadji C, Kundu SC. Engineered silk fibroin protein 3-D matrices for in vitro tumor model. Biomaterials. 2011 Mar; 32(8): 2149-59, 2011. doi: 10.1016/j.biomaterials.2010.11.052.

Hung TT; Chan J, Russell PJ, Power CA. Zoledronic acid preserves bone structure and increases survival but does not limit tumour incidence in a prostate cancer bone metastasis model. PLoS ONE. 2011; 6(5): e19389, 1-8, 2011. doi: 10.1371/journal.pone.0019389.

Singh P, Joshi S, Russell PJ, Verma N, Wang XC, Khatri A, Molecular chemotherapy and chemotherapy: A new front against late stage hormone refractory prostate cancer. Clinical Cancer Research. 2011 Jun 15; 17(12):4006-18. doi: 10.1158/1078-0432.CCR-11-0248.

Simanainen U, McNamara K, Gao YR, McPherson S, Desai R, Jimenez M, Handelsman DJ. Anterior prostate epithelial AR inactivation modifies estrogen receptor expression and increases estrogen sensitivity. Am J Physiol Endocrinol Metab. 2011 Oct;301(4):E727-35. doi: 10.1152/ajpendo.00580.2010.

Pokorny MR, Scott DJ. Do Maori and Pacific Islander men present with more advanced prostate cancer than European New Zealand men? An analysis of 486 men undergoing biopsy in Auckland. BJU Int. 2011 Apr; 107 Suppl 3:27-32. doi: 10.1111/j.1464-410X.2010.09988.x.

Suryadinata R, Sadowski M, Steel R and Sarcevic B. Cyclin-dependent Kinase-mediated phosphorylation of RBP1 and pRb promotes their dissociation to mediate release of the SAP30/mSin3/HDAC transcriptional repressor complex. J. Biol. Chem. 2011 Feb 18; 286(7):5108-18. doi: 10.1074/jbc.M110.198473.

Luk SU, Yap WN, Chiu YT, Lee DT, Ma S, Lee TK, Vasireddy RS, Wong YC, Ching YP, Nelson C, Yap YL, Ling MT. (2011) Gamma-tocotrienol as an effective agent in targeting prostate cancer stem cell-like population. Int J Cancer. 2011 May 1;128(9):2182-91. doi: 10.1002/ijc.25546.

Ling MT, Tay D, Cheung W, Ellis-Behnke R. Using self-assembled nanomaterials to delay the formation of metastatic cancer cell colonies in vitro. Cell Transplant. 2011;20(1):127-31. doi: 10.3727/096368910X532783.

2010

Haddad AQ, Fleshner N, Nelson C, Saour B, Musquera M, Venkateswaran V, Klotz L. Antiproliferative mechanisms of the flavonoids 2,2_-dihydroxychalcone and fisetin in human prostate cancer cells. N., 2010;62(5):668-81. doi: 10.1080/01635581003605524.

Lai J, Lehman ML, Dinger ME, Hendy SC, Mercer TR, Seim I, Lawrence MG, Mattick JS, Clements JA, Nelson CC. A variant of the KLK4 gene is expressed as a sense-antisense chimeric transcript in prostate cancer cells. RNA. 2010 Jun;16(6):1156-66. doi: 10.1261/rna.2019810.

Zoubeidi A, Ettinger S, Beraldi E, Hadaschik B, Zardan A, Klomp LW, Nelson CC, Rennie PS, Gleave ME. Clusterin facilitates COMMD1 and I-kappaB degradation to enhance NF-kappaB activity in prostate cancer cells. Mol Cancer Res. 2010 Jan;8(1):119-30. doi: 10.1158/1541-7786.MCR-09-0277.

Leon CG, Locke JA, Adomat HH, Etinger SL, Twiddy AL, Neumann RD, Nelson CC, Guns ES, Wasan KM. Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model.  Prostate. 2010 Mar 1;70(4):390-400. doi: 10.1002/pros.21072.

Locke JA, Tomlinson Guns ES, Lehman ML, Ettinger S, Zoubedi A, Lubik A, Margiotti K, Fazli L, Adomat H, Wasan KM, Gleave ME, and Nelson CC. Arachidonic acid activation of intratumoral steroid synthesis during prostate cancer progression to castration resistance. Prostate. 2010 Feb 15;70(3):239-51. doi: 10.1002/pros.21057.

Andrieu C, Taieb D, Baylot V, Ettinger S, Soubeyran P, De-Thonel A, Nelson C, Garrido C, So A, Fazli L, Bladou F, Gleave M, Iovanna J. L., and Rocchi P. Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E. Oncogene. 2010 Apr 1;29(13):1883-96. doi: 10.1038/onc.2009.479.

Whitbread K, Veveris-Lowe TL, Dong Y, Tan OL, Gardiner RA, Samaratunga HM, Nicol DL, Clements JA. Expression of PSA-RP2, an alternatively spliced variant from the PSA gene, is increased in prostate cancer tissues but the protein is not secreted from prostate cancer cells. Biol Chem 3rd International Kallikrein Symposium Special Issue. 2010 Apr; 391(4):461-6. doi: 10.1515/BC.2010.043.

Hutmacher DW, Loessner D, Rizzi S, Kaplan DL, Mooney DJ, Clements JA. Can tissue engineering concepts advance tumor biology research? Trends Biotechnol. 2010 Mar; 28(3):125-33. doi: 10.1016/j.tibtech.2009.12.001.

Lawrence MG, Lai J, Clements JA. Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus. Endocr Rev. 2010 Aug; 31(4):407-46. doi: 10.1210/er.2009-0034.

Ricciardelli C, Bianco-Miotto T, Jindal S, Dodd TJ, Cohen PA, Marshall VR, Sutherland PD, Samaratunga H, Kench J, Dong Y, Wang H, Clements JA, Risbridger GP, Tilley WD, Horsfall DJ, and the Australian Prostate Cancer BioResource. Comparative biomarker expression and RNA integrity in biospecimens derived from radical retropubic and robotic assisted laproscopic prostatectomies. Cancer Epidemiology Biomarkers & Prevention. 2010 Jul;19(7):1755-65. doi: 10.1158/1055-9965.EPI-10-0059.

Reichert JC, Quent VMC, Burke LJ, Stansfield SH, Clements JA, Hutmacher DW.  Mineralised human primary osteoblast matrices as a model system to analyse interactions of prostate cancer cells within the bone microenvironment.  Biomaterials. 2010 Nov;31(31):7928-36. doi: 10.1016/j.biomaterials.2010.06.055.

He Y, Wortmann A, Burke LJ, Reid JC, Adams MN, Abdul-Jabbar I, Quigley JP, Leduc R, Kirchhofer D, Hooper JD. Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta.  J Biol Chem. 2010 Aug 20;285(34):26162-73. doi: 10.1074/jbc.M109.096453.

Antalis TM, Buzza MS, Hodge KM, Hooper JD, Netzel-Arnett S. The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment. Biochem J. 2010 Jun 15; 428(3):325-46. doi: 10.1042/BJ20100046.

Bennett NC, Gardiner RA, Hooper JD, Johnson DW, Gobe GC. Molecular cell biology of androgen receptor signalling. Int J Biochem Cell Biol. 2010 Jun;42(6):813-27. doi: 10.1016/j.biocel.2009.11.013.

Hutmacher DWBiomaterials offer cancer research the third dimension. Nat Mater. 2010 Feb; 9(2):90-3. doi: 10.1038/nmat2619.

Quent VM, Loessner D, Friis T, Reichert JC, Hutmacher DW. Discrepancies between metabolic activity and DNA content as tool to assess cell proliferation in cancer research. J Cell Mol Med. 2010 Apr;14(4):1003-13. doi: 10.1111/j.1582-4934.2010.01013.x.

Sieh S, Lubik AA, Clements JA, Nelson CC, Hutmacher DW. Interactions between human osteoblasts and prostate cancer cells in a novel 3D in vitro model. Organogenesis. 2010 Jul-Sep;6(3):181-8.

Singh PP, Yam M, Russell PJ, Khatri, A. Molecular and traditional chemotherapy: a united front against prostate cancer. Cancer Lett. 2010 Jul 1;293(1):1-14. doi: 10.1016/j.canlet.2009.11.019.

You JJ, Fitzgerald A, Cozzi PJ, Zhao Z, Graham P, Russell PJ, Walsh BJ, WilcoxM, Wasinger V, Li Y. Post translational modification of proteins in tears. Electrophoresis. 2010 Jun;31(11):1853-61. doi: 10.1002/elps.200900755.

Scott KF, Sajinovic M, Hein J,  Nixdorf S, Galettis P, Liauw W, de Souza P, Dong Q, Graham GG, Russell PJ. Emerging roles for phospholipase A2 enzymes in cancer.  Biochimie. 2010 Jun;92(6):601-10. doi: 10.1016/j.biochi.2010.03.019.

de Souza PL, Russell PJ, Kearsley JH, Howes LG. Clinical pharmacology of isoflavones and its relevance for the potential treatment of prostate cancer. Nutr Rev. 2010 Sep;68(9):542-55. doi: 10.1111/j.1753-4887.2010.00314.x.

Tang C, Russell PJ, Martiniello-Wilks R, Rasko J, Khatri A. Concise review: Nanoparticles and cellular carriers-allies in cancer imaging and cellular gene therapy? Stem Cells. 2010 Sep;28(9):1686-702. doi: 10.1002/stem.473.

Yap WN, Zaiden N, Luk SY, Lee DT, Ling MT, Wong YC and Yap YL. In vivo evidence of gamma-tocotrienol as a chemosensitizer in the treatment of hormone-refractory prostate cancer. Pharmacology. 2010;85(4):248-58. doi: 10.1159/000278205.

Chua CW, Chiu YT, Yuen HF, Chan KW, Wang X, Ling MT, Wong YC. Differential expression of MSX2 in nodular hyperplasia, high-grade prostatic intraepithelial neoplasia and prostate adenocarcinoma. APMIS. 2010 Dec;118(12):918-26. doi: 10.1111/j.1600-0463.2010.02626.x.

Thompson VC, Hurtado-Coll A,  Turbin D,  Fazli L, Lehman M, Gleave M,  and Nelson C. Relaxin drives Wnt signaling through upregulation of PCDHY in prostate cancer. The Prostate. 2010 Jul 1;70(10):1134-45. doi: 10.1002/pros.21148. 

Mostaghel E, Nelson PS, Nelson C, Montgomery RB. Intraprostatic steroidogenic enzymes - letter.  Cancer Res. 2010 Oct 15;70(20):8247-9; author reply 8249-50. doi: 10.1158/0008-5472.CAN-10-1458.

Bianco-Miotto T, Chiam K, Buchanan G, Jindal S, Day TK, Thomas M, Pickering MA, O'Loughlin MA, Ryan NK, Raymond WA, Horvath LG, Kench JG, Stricker PD, Marshall VR, Sutherland RL, Henshall SM, Gerald WL, Scher HI, Risbridger GP, Clements JA, Butler LM, Tilley WD, Horsfall DJ, Ricciardelli C for the Australian Prostate Cancer BioResource. Global Levels of specific Histone Modifications and an Epigenetic Gene Signature predict prostate cancer progression and development. Cancer Epidemiol Biomarkers Prev. 2010 Oct;19(10):2611-22. doi: 10.1158/1055-9965.EPI-10-0555.

Hao J, Chen H, Madigan MC, Cozzi PJ, Beretov J, Xiao W, Delprado WJ, Russell PJ, Li Y. Co-expression of CD147 (EMMPRIN), CD44v3-10, MDR1 and monocarboxylate transporters is associated with prostate cancer drug resistance and progression. Br J Cancer. 2010 Sep 28;103(7):1008-18. doi: 10.1038/sj.bjc.6605839.

Li Y, Cozzi PJ, Russell PJ. Promising tumor-associated antigens for future prostate cancer therapy. Med Res Rev. 2010 Jan;30(1):67-101. doi: 10.1002/med.20165.

Yap WN, Zaiden N, Tan YL, Ngoh CP, Zhang XW, Wong YC, Ling MT, Yap YL. Id1, inhibitor of differentiation, is a key protein mediating anti-tumor responses of  gamma-tocotrienol in breast cancer cells. Cancer Lett. 2010 May 28;291(2):187-99. doi: 10.1016/j.canlet.2009.10.012.

2009

 Thierry B, Al-Ejeh F, Khatri A, Yuan Z, Russell PJ, Ping S, Brown MP, Majewski P. Multifunctional core-shell magnetic cisplatin nanocarriers. Chem Commun (Camb). 2009 Dec 21;(47):7348-50. doi: 10.1039/b911703b.

Li B, Tsao SW, Li YY, Wang X, Ling MT, Wong YC, He QY, Cheung AL. Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway. Int J Cancer. 2009 Dec 1;125(11):2576-85. doi: 10.1002/ijc.24675.

Power CA, Pwint H, Chan J, Cho J, Yu Y, Walsh W, Russell PJ. A novel model of bone-metastatic prostate cancer in immunocompetent mice. Prostate. 2009 Nov 1;69(15):1613-23. doi: 10.1002/pros.21010.

Farhadieh RD, Salardini A, Rees CG, Russell PJ, Yang JL, Smee R. Protein expression of epidermal growth factor receptor in laryngeal squamous cell carcinoma index tumors correlates with diagnosis of second primary tumors of the  upper aero-digestive tract. Ann Surg Oncol. 2009 Oct;16(10):2888-94. doi: 10.1245/s10434-009-0649-4.

Bennett N, Hooper JD, Lee CS, Gobe GC. Androgen receptor and caveolin-1 in prostate cancer. IUBMB Life. 2009 Oct;61(10):961-70. doi: 10.1002/iub.244.

Yi Y, Nandana S, Case T, Nelson C, Radmilovic T, Matusik RJ, Tsuchiya KD. Candidate metastasis suppressor genes uncovered by array comparative genomic hybridization in a mouse allograft model of prostate cancer. Mol Cytogenet. 2009 Sep 26;2:18. doi: 10.1186/1755-8166-2-18. PMID: 19781100

Telesca D, Inoue LY, Neira M, Etzioni R, Gleave M, Nelson C. Differential expression and network inferences through functional data modeling. Biometrics. 2009 Sep; 65(3):793-804. doi: 10.1111/j.1541-0420.2008.01159.x. Epub 2008 Nov 13. PMID: 19053995

Locke JA, Nelson CC, Adomat HH, Hendy SC, Gleave ME, Guns ES. Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts. J Steroid Biochem Mol Biol. 2009 Jul;115(3-5):126-36. doi: 10.1016/j.jsbmb.2009.03.011. Epub 2009 Apr 5.PMID: 19442514

Locke JA, Fazli L, Adomat H, Smyl J, Weins K, Lubik AA, Hales DB, Nelson CC, Gleave ME, Tomlinson Guns ES. A novel communication role for CYP17A1 in the progression of castration-resistant prostate cancer. Prostate. 2009 Jun 15;69(9):928-37. doi: 10.1002/pros.20940. PMID: 19267349

Khatri A, Husaini Y,  Ow K, Chapman J, Russell PJ. Cytosine Deaminase-Uracil Phosphoribosyl Transferase and Interleukin-12 and -18: a multimodal anticancer interface marked by specific modulation in serum cytokines. Clin Cancer Res. 2009 Mar 24; 15(7):2323-2234.

Snoek R, Cheng H, Margiotti K, Wafa LA, Wong CA, Wong EC, Fazli L, Nelson CC, Gleave ME, Rennie PS. In vivo knockdown of the androgen receptor results in growth inhibition and regression of well-established, castration-resistant prostate tumors. Clin Cancer Res. 2009 Jan 1;15(1):39-47. doi: 10.1158/1078-0432.CCR-08-1726. PMID:19118031

Karst AM, Gao K, Nelson CC, Li G. Nuclear factor kappa B subunit p50 promotes melanoma angiogenesis by upregulating interleukin-6 expression. Int J Cancer. 2009 Jan 15;124(2):494-501. doi: 10.1002/ijc.23973. PMID: 18942706

Read JT, Cheng H, Hendy SC, Nelson CC, Rennie PS. Receptor-DNA interactions: EMSA and footprinting. Methods Mol Biol. 2009;505:97-122. doi: 10.1007/978-1-60327-575-0_6. PMID: 19117141

Day TK, Nelson CC, Gleave ME. Differential Regulation of Clusterin Isoforms by the Androgen Receptor. In Mohler, James & Tindall, Donald (Eds.) Androgen Action in Prostate Cancer. Springer US. 2009 Mar 27. pp. 681-700. doi: 10.1007/978-0-387-69179-4_29