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About Us

Lisa Philp

Lisa Philp

Positions

  • Postdoctoral Research Fellow (Adipokines), APCRC-Q
  • Advance Queensland Industry Research Fellow - Translational Adipokine Research Group, APCRC-Q
  • Centre for Genomics and Personalised Health, QUT
  • School of Biomedical Sciences, Faculty of Health, QUT

Contact Details

Linkedin profile
https://au.linkedin.com/in/lisa-k-philp

Qualifications

  • PhD, Medicine, University of Adelaide, South Australia, 2011
  • BSc, Hons (First Class), Physiology, University of Adelaide, South Australia, 2006
  • BSc Biomedical Science, University of Adelaide, South Australia, 2005

Biography

Dr Lisa Philp heads the Translational Adipokine Research group, within the Australian Prostate Cancer Research Centre – Queensland, based at the Translational Research Institute, Brisbane. Dr Philp originates from a metabolic research background with doctoral and undergraduate training in obesity, nutrition and endocrinology at the University of Adelaide, South Australia. Post-PhD, Dr Philp has built a research career studying endocrine-driven prostate cancer, focusing on the intersection between chronic metabolic dysfunction and the androgen axis in prostate cancer. She has a keen interest in the link between the adaptive adipokine and metabolic hormone changes triggered by androgen targeted therapies, and their role in prostate cancer progression. Dr Philp’s current industry-linked research program, funded by the US Department of Defense and Movember, includes the rigorous preclinical development of new therapeutics targeting adipokine signalling, as a novel treatment modality to combat late-stage metastatic prostate cancer and hopefully overcome treatment resistant disease. Recently Dr Philp was also awarded an Advance Queensland Industry Research Fellowship to develop adipokine targeted therapeutics for the treatment of acute respiratory distress syndrome and COVID-19.

Awards and grants

2014

University of Adelaide Discipline of Medicine Staff Travel Award

2012

Australian Society for Medical Research Annual Scientific Meeting Best Poster    Award (Early Career Researcher)

2010

Australian and New Zealand Obesity Society Student Travel Award

2010

University of Adelaide Faculty of Health Sciences Postgraduate Travel Fellowship

2009

Australian and New Zealand Obesity Society Student Travel Award

2008

Australian and New Zealand Obesity Society Student Travel Award

2007-10 

  Australian Postgraduate Award, PhD (Medicine) University of Adelaide

2006

University of Adelaide School of Molecular and Biomedical Science Honours Research Scholarship

2005-6

Child Health Research Institute Summer Scholarship

2004-5

University of Adelaide School of Molecular and Biomedical Science Summer Research Scholarship

Research interests

Prostate cancer, adipokines, drug development, preclinical modelling, preclinical imaging, metabolism, metabolic syndrome, physiology

Current research projects

Understanding endocrine-related adaptive responses stemming from the progression of prostate cancer to androgen-independence

Top publications

Philp LK, Rockstroh A, Sadowski MC, Taherian Fard A, Lehman M, Tevz G, Libério MS, Bidgood CL, Gunter JH, McPherson S, Bartonicek N, Wade JD, Otvos L, Nelson CC. Leptin antagonism inhibits prostate cancer xenograft growth and progression. Endocr Relat Cancer. 2021 Apr 29;28(5):353-375. doi: 10.1530/ERC-20-0405. PMID: 33794502.
Philp LK, Rockstroh A, Lehman M, Sadowski MC, Bartonicek N, Wade JD, Otvos L, Nelson CC. Adiponectin receptor activation inhibits prostate cancer xenograft growth. Endocr Relat Cancer. 2020 Dec;27(12):711-729. doi: 10.1530/ERC-20-0297. PMID: 33112829.
Tousignant KD, Rockstroh A, Taherian Fard A, Lehman ML, Wang C, McPherson SJ, Philp LK, Bartonicek N, Dinger ME, Nelson CC, Sadowski MC. Lipid Uptake Is an Androgen-Enhanced Lipid Supply Pathway Associated with Prostate Cancer Disease Progression and Bone Metastasis. Mol Cancer Res. 2019 May;17(5):1166-1179. doi: 10.1158/1541-7786.MCR-18-1147. Epub 2019 Feb 26. PMID: 30808729.
Philp LK, Day TK, Butler MS, Laven-Law G, Jindal S, Hickey TE, Scher HI, Butler LM, Tilley WD. Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha (SGTA) Ablation Limits Offspring Viability and Growth in Mice. Sci Rep. 2016 Jun 30;6:28950. doi: 10.1038/srep28950. PMID: 27358191; PMCID: PMC4928056.
Philp LK, Heilbronn LK, Janovska A, Wittert GA. Dietary enrichment with fish oil prevents high fat-induced metabolic dysfunction in skeletal muscle in mice. PLoS One. 2015 Feb 6;10(2):e0117494. doi: 10.1371/journal.pone.0117494. PMID: 25658742; PMCID: PMC4320112.
More publications are available at pubmed.
More publications are available on PubMed

Team

Collaborators

Professional memberships and associations

2014-present

The Endocrine Society

2014-present

Endocrine Society of Australia

2011-present   

Australian Society of Medical Research

2007-11

Australian and New Zealand Obesity Society

2006

Perinatal Society of Australia and New Zealand

2003-present

Golden Key International Honour Society