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Translational Research

Presentations 2019

In 2019, APCRC-Q research fellows and students presented orals and posters at the following national and international conferences:

Brisbane Cancer Conference, 28-29 November 2019:

          Invited speaker: Gunter J, Adaptive prostate cancer cell metabolism following
          combined anti-androgen and biguanide treatment

          Invited speaker: Hollier B, Therapeutic targeting of treatment-induced anaplastic
          phenotypes in prostate cancer

          Invited speaker: Vela I, Mock Queensland Molecular Tumour Board Meeting, Case
          Presentation & Discussion

          Invited speaker: Alinezhad S, Predictive therapeutic screening in high risk localized
          prostate cancer

Poster and 3-minute lightning oral presentation: Haque M, Repurposing biguanide with anti-androgen to combat adaptive response in advanced prostate cancer, EMBL Australia Postgraduate Symposium 2019, Victorian Comprehensive Cancer Centre, Melbourne, 27-29 November 2019

Poster: Bock N, Engineered osteoblastic metastases reveal in vitro osteomimicry of patient-derived xenografts and the effects of androgen deprivation therapies in bone metastatic prostate cancer, Good Bye Flat Biology: Advancing 3D-based Models for Cancer Biology and Drug Discovery, European Association for Cancer Research (EACR), Berlin, Germany, November 2019

Invited speaker: Hollier B, Therapeutic targeting of treatment-induced anaplastic phenotypes in prostate cancer, Indo-Australia EMT Symposium, Adelaide, 19 November 2019

Poster: Williams ED, Epithelial mesenchymal plasticity in circulating tumour cells from prostate cancer PDX models, The 9th EMT International Association Meeting, Kumamoto, Japan, 11-14 November 2019

Oral: Williams ED, Epithelial mesenchymal plasticity in circulating tumour cells from prostate cancer PDX models, Australian Metastasis Society (OzMRS) Meeting held in conjunction with COGNO and the Thomas Ashworth Symposium, Sydney, 30 October 2019

Plenary speaker: Clements J, From mice to men – kallikreins on steroids: Insights into the roles of the kallikrein related (KLK) peptidases in hormone dependent cancer, 11th General Meeting of the International Proteolysis Society - ´Interfaces in Proteolysis´, Mariánské Lázně, Czech Republic, October 2019

Invited speaker: Clements J, KLK14 and the adaptive response to Androgen Targeted Therapies (ATT) in prostate cancer, ASBMB Special Symposium on Serine Proteases in Pericellular Proteolysis and Signaling, Potomac, Maryland, USA, September 2019

Invited speaker: Clements J, Differential role of KLK peptidases in prostate cancer - Proteases, inhibitors and new therapy concepts in cancer and other diseases, DAAD Mini Symposium, Munich, Germany, September 2019

Oral: Bidgood CL, Investigating the role of branched chain amino acid metabolism in the development of prostate cancer therapy resistance. QUT Postgraduate Symposium, Brisbane, 13 September 2019 and TRI Student Seminar Series, Brisbane, 15 August 2019

 

IHBI Inspires Postgraduate Conference, Brisbane Convention and Exhibition Centre, 11-12 August 2019:

          Poster and 1-minute lightning oral presentation: Haque M, Targeting metabolic
          responses in advanced prostate cancer following anti-androgen and biguanide co-
          treatment

          Poster: Bidgood CL, High-content screening of small molecule inhibitors from the
          Australian biota targeting prostate cancer metabolism


TRI Symposium, Brisbane, 5-6 August 2019:

          Poster: Haque M, Targeting adaptive response in advance prostate cancer with
          combined anti-androgen and biguanide treatment

          Poster and 1-minute lightening oral presentation: Bidgood CL, High-content
          screening of small molecule inhibitors from the Australian biota targeting prostate
          cancer metabolism

          Poster: Alinezhad S, Introduction of shRNA targeting androgen receptor inhibit
          tumour growth in prostate cancer patient-derived xenografts

          Oral and Poster: Thomas P, Detection of gonorrhoeae in prostate cancer tissue,
          Winner Translational Science Prize, Runner-up Professional Poster Prize (Discover
          Category)

Poster and Rapid-Fire Talk: Bock N, Cancer cell osteomimicry revealed using bioengineering and patient-derived xenografts, Biomimetics in Bioengineering, Brisbane, 4-6 August 2019. Poster Presentation Award.

 

PA Hospital Health Symposium, Brisbane, 30 July - 2 August 2019:

          Poster: Thomas P, Detection of gonorrhoeae in prostate cancer tissue, Early-Career
          Best Poster Basic/Laboratory Science Research Excellence Award Winner

          Poster: Haque M, Targeting adaptive response in advance prostate cancer with
          combined anti-androgen and biguanide treatment

Invited speaker: Gunter J, Adaptive prostate cancer cell metabolism following combined anti-androgen and biguanide treatment, QIMR Cancer Seminar, Brisbane, 30 July 2019

Invited speaker: Thomas P, Gonorrhoeae infection and prostate cancer risk, Queensland Australasian Association for Clinical Biochemistry and Laboratory Medicine (AACB) Branch Weekend Meeting, Brisbane, 20-21 July 2019

Oral: Philp L, The Link Between Body Fat Hormones & Prostate Cancer Progression, BLiSS - Brisbane Life Science ECR Symposium, June 2019

 

3rd Australian Cancer and Metabolism Meeting, Sydney, 20-22 May 2019:

          Invited speaker: Gunter J, Adaptive prostate cancer cell metabolism following
          combined anti-androgen and biguanide treatment

          Invited speaker: Sadowski M, Multiparametric quantitative single cell imaging to
          illuminate prostate cancer metabolism with subcellular precision

          Poster: Tousignant K, The fat side of Enzalutamide: Extensive lipid remodelling
          fuelled by lipid uptake is an early mechanism of resistance to androgen receptor-
          targeted therapies in prostate cancer.
Winner of poster competition

          Poster: Tousignant K, Lipid uptake is an androgen-enhanced lipid supply pathway
          associated with prostate cancer disease progression and bone metastasis

          Oral: Philp L, Adiponectin Receptor Agonist Slows the Progression of Advanced
          Prostate Cancer

Oral: Gunter J, Adaptive prostate cancer cell metabolism following combined anti-androgen and biguanide treatment, TRI Cancer Seminar, Brisbane, 16 May 2019

Oral: Gunter J, Adaptive prostate cancer cell metabolism following combined anti-androgen and biguanide treatment. Canceropole-paca, 3rd Edition of Metabolism & Cancer Conference, Marseille, France, 1-2 April 2019

Poster: Bock N, Biofabricated 3D composites of hydrogels, melt electrowritten scaffolds and primary cells for human bone tissue engineering, Australasian Society of Biomaterials and Tissue Engineering (ASBTE) ECR workshop, Sydney, April 2019

Invited speaker: Clements J, KLK serine peptidases and their role in the tumour microenvironment, UQ Pharmacy School Seminar series, March 2019

Poster: Hollier BG, A molecular portrait of epithelial–mesenchymal plasticity in prostate cancer associated with clinical outcome, 7th International PacRim Breast and Prostate Cancer Meeting, Barossa Novotel, South Australia, 17-20 March 2019