Sally-Anne Stephenson
Positions
- Lecturer, Faculty of Health, QUT
- Group Leader, Eph Receptor Biology Group, Cancer Research Program, Cells and Tissues Domain, IHBI, QUT
Related websites and profiles
Qualifications
- 1998, Doctor of Philosophy, University of Queensland, Australia
- 1992, Bachelor of Science (Hons 1), University of Queensland, Australia
- 1991, Bachelor of Science, University of Queensland, Australia
Biography
The main research interest of the Eph receptor biology group that Dr Stephenson runs is the EphB4 receptor tyrosine kinase and its contribution to epithelial cancers. Currently, they are developing monoclonal antibodies targeting this protein for testing as potential anti-cancer therapeutics.
Along with her research activities at QUT, Dr Stephenson is a Lecturer in the School of Life Sciences. She is the Chief Scientific Officer of BenEphex Biotechnologies Pty Ltd in Adelaide, and in 2006 received the Woman of Distinction in Medical Research Award from the Asia Pacific Business Council for Women.
Awards and grants
Awards
| 1993 | Australian Post-graduate Research Award |
| 1993 | Co-operative Research Centre for Tropical Plant Pathology Research Award |
| 2003 | Cancer Council of South Australia, Senior Research Fellowship |
| 2006 | Asia Pacific Business Council for Women, Woman of distinction in Medical Research Award |
| 2006 | Peer-Nominated Female Leader in Science Engineering and Technology, Bragg Initiative, South Australian Government |
| 2009 | Nominated for an Excellence in Teaching - Students' Choice Award |
| 2010 | Vice Chancellor's Performance Award, Teaching |
| 2010 | Nomianated for QUT STEM Postgraduate supervisor Award |
| 2011 | Nominated QUT STEM Postgraduate Supervisor Award |
| 2011 | Nominated for Women in Technology Biotech Research Award |
Grants
| ECARD Research Grant |
Research interests
EphB4, Eph receptor tyrosine kinases, epithelial cancers
Current research projects
1. Nuclear localization of EphB4 in prostate cancer cells
2. Protease regulation of EphB4 on the surface of cancer cells
3. EphB4-protein interactions during ligand-independent and ligand-dependent signaling
Top publications
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Stephenson, S., Verity, K., Ashworth. L.A., and Clements, J.A. (1999) Localisation of a new prostate-specific antigen-related serine protease gene, KLK4, is evidence for an expanded human kallikrein gene family cluster on chromosome 19q13.3-13.4. The Journal of Biological Chemistry 274(33): 23210 – 23214. JIF 5.520, 41/276 Biochemistry and Molecular Biology.
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Harvey, T.J., Hooper, J.D., Myers, S.A., Stephenson, S, Ashworth, L.K. and Clements, J.A. (2000) Tissue-specific expression patterns and fine mapping of the human Kallikrein (KLK) locus on proximal 19q13.4. The Journal of Biological Chemistry 275(48): 37397 – 37406. JIF 5.520, 41/276 Biochemistry and Molecular Biology.
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Rae, F.K., Stephenson, S.A., Nicol, D.L. and Clements, J.A. (2000) Identification of eight new genes associated with renal cell carcinoma using differential display. International Journal of Cancer 88(5): 726 – 732. JIF - 4.734, 30/141 Oncology.
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Stephenson, S., Slomka, S., Douglas, E.L., Hewett, P.J. and Hardingham, J.E. (2001) Receptor protein tyrosine kinase EphB4 is up-regulated in colon cancer. Biomed Central – Molecular Biology 2:15. JIF – 3.115, 93/261 Biochemistry and Molecular Biology.
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Lee Y, Perren J, Douglas E, Raynor M, Bartley M, Bardy P and Stephenson S. (2005) Investigation of the expression of EphB4 receptor tyrosine kinase in prostate carcinoma. BMC Cancer, 5:119. JIF – 3.087, 59/141 Oncology.
Team
- Professor Adrian Herington
- Dr Inga Mertens-Walker
- Mr Raphael Rutkowski
- Miss Jessica Lisle
Collaborators
- Dr Andrew Brooks, UQ
- Professor Mike Waters, UQ
- Professor David Jans, Monash
Professional memberships and associations
| 1993 - | Australian Society for Biochemistry and Molecular Biology |
| 1998 - | Australian Society for Medical Research
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