Judith Clements AC

Distinguished Professor Clements has over 30 years of experience as a molecular and cell biologist in the endocrine field with expertise in neuroendocrine functional peptides and proteases – particularly the kallikrein-like serine protease family - in hormone dependent cancers, with a major emphasis on prostate cancer. She has published over 190 articles in refereed international journals and book chapters and has an H-index of 45 with >7000 career citations (Google Scholar).

Her research covers the spectrum of biochemistry, cellular and molecular biology, using both in vitro and in vivo cell models, and includes proteomic, transcriptomic and genetic studies and the development and use of 3-dimensional cell culture systems better mimicking the tumour microenvironment. Her work encompasses understanding the regulation of endocrine/paracrine and autocrine mechanisms underpinning prostate cancer maintenance and progression and the identification of potential new diagnostic, prognostic and therapeutic targets. She is internationally recognised as an expert in her field and has been awarded the Silver and Gold medals of the international Frey-Werle Foundation for her work. She leads the Queensland node of the international PRACTICAL consortium, has led the Australian Prostate Cancer BioResource (tissue bank) for more than 10 years and is Chair of the Queensland Board of the PCFA.

From a career total of 170

• Clements JA, Fuller PJ, Mc Nally M, Nikolaidis I and Funder JW.  Estrogen regulation of kallikrein gene expression in the rat anterior pituitary.  Endocrinology 119: 268–273, 1986.
• Clements JA, Matheson BA, Wines DR, Brady JM, Mac Donald RJ and Funder JW.  Androgen dependence of specific kallikrein gene family members expressed in rat prostate.  J. Biol. Chem. 263: 16132–16137, 1988.
• Fuller PJ, Matheson BA, Verity K and Clements JA. Kallikrein gene expression in estrogen–induced pituitary tumors.  Mol. Cell. Endocrinol. 60: 225–232, 1988.
• Clements JA. The glandular kallikrein family of enzymes: tissue–specific expression and hormonal regulation.  Endocrine Reviews, 10: 393–419, 1989.
• Clements JA, Matheson BA and Funder JW.  Tissue–specific developmental expression of the kallikrein gene family in the rat.  J. Biol. Chem. 265: 1077–1081, 1990.

• Dr Karen Chambers, Senior Research Assistant
• Dr Ying Dong, Research Fellow
• Miss Ruth Fuhrman-Luck, PhD Student
• Dr Daniela Loessner, Postdoctoral Fellow
• Miss Munasinghage Silva, PhD Student
• Srilakshmi Srinavasan, Research Assistant
• Dr Shane Stegeman, Postdoctoral Research Fellow
• Mr Carson Stephens, Research Assistant
• Tracy O'Mara
• Grace Eng
• Dr Trina Yeadon, National Project Manager

• Dr Viktor Magdalen, KliFlo der Frauenklinik, Munich, Germany
• Dr David Kaplan, Tufts University, Boston, USA
• Drs Stephen Chanock & Laufey Amundattoir, NCI/NIH, Bethesda, Maryland, USA
• Dr Matthias Lutholf, Ecole de Polytechnic, Lausanne, Switzerland
• Prof Ros Eeles, University College, London, UK
• Prof Chris Overall, UBC, Vancouver, Canada
• Prof Wayne Tilley, Hanson Cancer Centre, Adelaide
• Prof Gail Risbridger, Monash University, Melbourne
• Dr Oded Kleifeld, Monash University, Melbourne
• Dr Amanda Spurdle, QIMR, Brisbane
• Drs Peter Parsons & Glen Boyle, QIMR, Brisbane
• Drs Jim Nicklin & Andreas Obermair, Wesley and Royal Brisbane & Women's Hospitals, Brisbane
• Dr H Samarantunga, Aquesta Pathology, brisbane
• Dr Jon Harris, IHBI, QUT, Brisbane
• Dr Mike Doran, IHBI, QUT, Brisbane
• A/Prof John Hooper, MMRI