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Grants

Metastatic prostate cancer and circulating tumour cell in vitro culture

The ability to grow metastatic prostate cells and Circulating Tumour Cells (CTCs) will provide multiple new model systems to investigate the mechanisms of cancer metastasis, identify new potential therapeutic targets and treatments, and from a precision medicine perspective, it may in the future provide an ability to tailor therapeutic decisions specific to each tumour prior to treating the patient. The potential utility of a "liquid biopsy" via culture, amplification and analysis of CTCs may avoid invasive biopsies of metastatic sites.

The aims of this project are:

  1. Establishment of organoid technology for metastatic prostate cancer tissue culture at PAH/APCRC-Q.
  2. Establishment of organoid technology for the culture, amplification and analysis of prostate cancer circulating tumour cells at PAH/APCRC-Q.
  3. Utilization of organoid culture technologies in Precision Medicine/Clinical Trials.

Investigators

Ian Vela APCRC-Q, IHBI, QUT, TRI & PAH

Duration

2015 - 2016

Funding

Upcoming Events

Jul 19, 2020 - Jul 21, 2020 ANZUP 2020 Annual Scientific Meeting
Adelaide Convention Centre, South Australia
Aug 18, 2020 - Aug 21, 2020 PA Hospital Health Symposium
Russell Strong Auditorium, Princess Alexandra Hospital, 199 Ipswich Rd, Woolloongabba
Aug 21, 2020 - Aug 23, 2020 21st Asia-Pacific Prostate Cancer Conference
Melbourne Convention and Exhibition Centre, Victoria
Sep 29, 2020 - Oct 02, 2020 ComBio 2020
Melbourne Convention and Exhibition Centre, Victoria
Nov 11, 2020 - Nov 13, 2020 COSA Annual Scientific Meeting
Brisbane Convention and Exhibition Centre, Queensland