High-content screening of small molecule inhibitors from nature that target prostate cancer metabolism

This project will screen and evaluate a library of 472 novel compounds that were isolated from Australian plants, fungi and marine organisms for their inhibitory activity on several metabolic pathways critical for prostate cancer growth and survival. This project will identify new metabolic inhibitors from nature, provide valuable insights for future large-scale cancer metabolism screens, generate knowledge about regulatory pathways of cancer metabolism and inform and inspire the development of new anticancer agents from nature. 



Rohan Davis Griffith Institute for Drug Discovery, APCRC-Q
Colleen Nelson APCRC-Q, IHBI, QUT, TRI
Martin Sadowski APCRC-Q, IHBI, QUT, TRI
Jennifer Gunter APCRC-Q, IHBI, QUT, TRI

Administering Institution

Griffith University


2017 - 2017



Prostate Cancer Foundation of Australia $99618

Upcoming Events

Feb 09, 2020 - Feb 13, 2020 ICONN 2020
Brisbane Convention and Exhibition Centre, Queensland
Feb 13, 2020 - Feb 15, 2020 ASCO Genitourinary Cancers Symposium 2020
Moscone West Building, San Francisco, USA
Mar 07, 2020 - Mar 10, 2020 USANZ 2020 Annual Scientific Meeting
International Convention Centre, Sydney, New South Wales
Mar 20, 2020 - Mar 24, 2020 EAU Congress 2020
RAI Amsterdam, The Netherlands
Mar 25, 2020 - Mar 29, 2020 World Science Festival Brisbane