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About Us

Sonika Tyagi

Sonika Tyagi

Positions

  • Bioinformatician

Contact Details

Qualifications

PhD, Bioinformatics, Jawaharlal Nehru University, India, 2007

Postgraduate Diploma, Bioinformatics, Jawaharlal Nehru University, India, 2002

MSc, Life Sciences, Jawaharlal Nehru University, India, 2001

BSc, CCS University Meerut UP, India, 1999

Biography

Dr Sonika Tyagi is a Bioinformatician who obtained her Advanced Postgraduate Diploma and PhD in Bioinformatics from the Jawaharlal Nehru University in New Delhi, India. During her PhD she received a research exchange award to visit University of Queensland in Australia and worked with Dr Tim Bailey at the Institute for Molecular Biosciences.

Her research focus is on developing computational methods to retrieve knowledge from vast amount of data being generated using high throughput techniques and biological experiments. She has developed bioinformatics tools and applications using machine learning, data mining and statistical approaches. These software tools are open source and available to users via free web interfaces.

From November 2010 to May 2011, she worked for the Australian Prostate Cancer Research Centre- Queensland in the role of a biostatistician.

Research interests

oncogenomics, miRNA and miRNA target prediction, microarray data analysis and next-generation sequence annotation

Top publications

  • Sonika Tyagi, Mitchell S. Stark, Nicholas K. Hayward, David C. Whiteman and Derek J. Nancarrow webFOG: A web tool to Map Genomic Features on to Genes, Biochem Biophys Res Commun. 2010 Oct 22;401(3):447-50. Epub 2010 Sep 24
  • Natalia K. Botelho, Fiona I. Schneiders, Sarah J. Lord, Araluen Freeman, Sonika Tyagi, Derek Nancarrow, Nicholas Hayward, David Whiteman, Reginald V. N. Lord. Alterations in gene expression in Barrett’s esophagus and esophageal adenocarcinoma measured by multiplexed tandem PCR in formalin-fixed, paraffin-embedded tissues. Cancer Biol Ther. 2010 Jul 26;10(2). [Epub ahead of print]
  • Mitchell S Stark, Sonika Tyagi, Derek J Nancarrow, Glen M Boyle, Andrew L Cook, David C Whiteman, Peter G Parsons, Chris Schmidt, RA Sturm, Nicholas K Hayward:  Characterization of the melanoma miRNAome by deep sequencing. PLosONE 2010, 5:e9685
  • Sonika Tyagi, Candida Vaz, Vipin Gupta, Rohit Bhatia, SN Maheshwari, Ashwin Srinivasan, Alok Bhattacharya: CID-miRNA: A web server for prediction of novel miRNA precursors in human genome. Biochemical and Biophysical Research Communications 2008, 372:831-834
  • Sonika Tyagi, Candida Vaz, Alok Bhattacharya:  Non–Coding RNAs and their Role in Biology Biobytes ISSN0971327, Vol 2 November 2007
  • Soma Ghosh, S. Satish, Sonika Tyagi, Alok Bhattacharya, and Sudha Bhattachary: Differential use of multiple replication origins in the ribosomal DNA episome of the protozoan parasite Entamoeba histolytica Nucleic Acid Research 2003, Vol. 31, No. 8 2035-2044.