Katrina Pirlo
Positions
- Research Assistant, APCRC-Q
- Member, IHBI, QUT
Qualifications
- BSc (Biotech) Hons 1A, The University of Newcastle, Australia, 2003
- BSc (Biotech), The University of Newcastle, Australia 2001
Biography
Katrina worked in both the Department of Physiology and Pharmacology, and the Department of Botany at The University of Queensland from 2003-2006.
In 2006, she moved to the UK where she worked at the Institute of Psychology, Kings College London for 18 months.
Following this she took up a 3 year role as a Research Assistant at Barts Cancer Institute, Queen Mary University London. Her project focused on viral gene therapy for the treatment of ovarian cancer.
Ms Pirlo joined the APCRC-Q in May 2014 where she investigates the mechanisms of plasticity in prostate cancer.
Awards and grants
Grants
|
2012-2014 |
National Health and Medical Research Council |
The role of angiopoietin-1 in the self renewal and metastasis of prostate cancer stem cells |
P Ling, J Clements, C Nelson |
Research interests
epithelial to mesenchymal transition, prostate cancer, plasticity
Top publications
- Young AM, Archibald KM, Tookman LA, Pool A, Dudek K, Jones C, Williams SL, Pirlo KJ, Willis AE, Lockley M, McNeish IA. Failure of translation of human adenovirus mRNA in murine cancer cells can be partially overcome by L4-100K expression in vitro & in vivo. Mol Ther. 2012 Sep;20(9):1676-88.
- C.M. Connell, A. Shibata, L. Tookman, K. Archibald, M.B. Flak, K. Pirlo, M. Lockley, S. Wheatley, I.A. McNeish. Genomic DNA damage and ATR-Chk1 signalling determine oncolytic adenoviral efficacy in human ovarian cancer. J Clin Invest. 2011 Apr;121(4):1283-97.
- Salako MA, Kulbe H, Ingemarsdotter CK, Pirlo KJ, Williams SL, Lockley M, Balkwill FR, McNeish IA. Inhibition of the Inflammatory Cytokine TNF-α Increases Adenovirus Activity in Ovarian Cancer via Modulation of cIAP1/2 Expression. Mol Ther. 2011 Mar;19(3):490-9.
- Flak MB, Connell CM, Chelala C, Archibald K, Salako MA, Pirlo KJ, Lockley M, Wheatley SP, Balkwill FR, McNeish IA. p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker. Mol Cancer. 2010 Jul 3;9:175. doi: 10.1186/1476-4598-9-175.
- Dawson PA, Pirlo KJ, Steane SE, Kunzelmann K, Chien YJ, Markovich D. Molecular cloning and characterization of the mouse Na+ sulfate cotransporter gene (Slc13a4): Structure and expression. Genes Genet Syst. 2006 Aug;81(4):265-72.
