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About Us

Christin Gasch

Positions

  • Postdoctoral Research Fellow, APCRC-Q
  • Member, IHBI, QUT

Contact Details

Phone
+61 7 3443 7264

Qualifications

Doctor of Science, University Medical Center Hamburg-Eppendorf, Germany, 2012

Diploma in Biology, University of Hamburg, Germany, 2008

Biography

Dr Gasch obtained her degree in biology from the University of Hamburg, Germany in 2008.

At the Institute of Tumour Biology, University Medical-Centre Hamburg Eppendorf Dr Gasch conducted her doctoral research project ‘Detection and characterisation of circulating tumour cells from the peripheral blood of patients with colorectal cancer’ for which she has been awarded the Doctor of Science in 2012.  

In 2013, Dr Gasch received a German research foundation (DFG) fellowship for studying the role of cell-based microRNA expression in therapy response of patients with colorectal cancer.  She began her work on this collaborative research program at Deakin University, Australia in 2014.

In 2016, Dr Gasch was able to transfer the DFG fellowship to the Australian Prostate Cancer Research Centre-Queensland where she continues to study circulating tumour cells in the peripheral blood as a diagnostic marker of clinical course and outcome.

Awards and grants

2013-2016    

DFG (German Research Foundation) Postdoctoral Research Fellowship

Research interests

Circulating tumour cells, metastasis, single cell analysis, tumour heterogeneity, microRNA

Top publications

Gasch C*, Plummer PN*, Jovanovic L, McInnes LM, Wescott D, Saunders CM, Schneeweiss A, Wallwiener M, Nelson C, Spring K, Riethdorf S, Thompson EW, Pantel K, Mellick AS. Heterogeneity of miR-10b expression in circulating tumor cells. Scientific Reports. 2015 Nov 2;5:15980* these authors contributed equally.

Müller C, Holtschmidt J, Auer M, Heitzer E, Lamszus K, Schulte A, Matschke J, Langer-Freitag S, Gasch C, Stoupiec M, Mauermann O, Peine S, Glatzel M, Speicher MR, Geigl JB, Westphal M, Pantel K, Riethdorf S. Hematogenous dissemination of glioblastoma multiforme. Science Transl. Med., 2014 Jul 30;6(247):247ra101.

Heitzer E,* Auer M*,  Hoffmann EM*, Pichler M*, Gasch C, Ulz P, Lax S, Waldispuehl-Geigl J, Mauermann O, Mohan S, Pristauz G, Lackner C, Höfler G, Eisner F, Petru E, Sill H, Samonigg H, Pantel K, Riethdorf S, Bauernhofer T, Geigl JB, Speicher MR. Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer, International J of Cancer, 2013 Jul 15;133(2):346-56. *these authors contributed equally

 Heitzer E,* Auer M*, Gasch C*, Pichler M*, Ulz P, Hoffmann EM, Lax S, Waldispuehl-Geigl J, Mauermann O, Lackner C, Höfler G, Eisner F, Sill H, Samonigg H, Pantel K, Riethdorf S, Bauernhofer T, Geigl JB, Speicher MR. Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing. Cancer Research, 2013 May 15;73(10):2965-75. *these authors contributed equally

 Gasch C, Langer S, Bauernhofer T, Reeh M, Seifert A, Mauermann O, Pantel K, Riethdorf S. Heterogeneity of Epidermal Growth Factor Receptor Status and Mutations of KRAS/PIK3CA in Circulating Tumor Cells of Patients with Colorectal Cancer. Clinical Chemistry, 2013 Jan;59(1):252-60.